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4-Aminobenzophenone

4-Aminobenzophenone structure

CAS No:
1137-41-3
Formula:
C13H11NO
Chemical Name:
4-Aminobenzophenone
Synonyms:
Methanone,(4-aminophenyl)phenyl-;Benzophenone,4-amino-;(4-Aminophenyl)phenylmethanone;p-Aminobenzophenone;4-Aminobenzophenone;p-Benzoylaniline;4-Benzoylbenzenamine;4-Benzoylaniline;NSC 7665
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

4-Aminobenzophenone, also known as p-aminobenzophenone, is an organic compound with the formula C₁₃H₁₁NO. The compound consists of a phenyl group and a phenyl ketone group, which are linked together by a nitrogen atom. 4-Aminobenzophenone usually appears in a yellowish solid form and has a characteristic aromatic odor. As an important organic intermediate, 4-Aminobenzophenone has been widely used in the chemical industry. It is widely used in the synthesis of dyes, drugs and many other organic compounds. Due to its molecular structure containing both an amino group (-NH₂) and a keto group (C=O), 4-Aminobenzophenone exhibits extremely high reactivity in chemical reactions. The amino functional group enables the compound to participate in a variety of substitution reactions, thus playing an important role in the field of organic synthesis and materials science. The versatility of this compound makes it an integral part of chemical research and industrial production.

4-Aminobenzophenone Basic Attributes

Molecular Weight：

197.23

Exact Mass：

197.23

BRN：

389292

EC Number：

214-506-6

UNII：

9VH7LQN5JE

NSC Number：

7665

DSSTox ID：

DTXSID8061557

HScode：

29223990

Characteristics

PSA：

43.1

XLogP3：

2.7

Appearance：

Yellow Fine Crystalline Powder

Density：

1.0957 (rough estimate)

Melting Point：

121-124 °C

Boiling Point：

246 °C (12.7517 mmHg)

Flash Point：

245-247°C/22mm

Refractive Index：

1.6050 (estimate)

Water Solubility：

Soluble in cold water, alcohol and ether.

Storage Conditions：

Store below +30°C.

Vapor Pressure：

9.42E-06mmHg at 25°C

Toxicity：

Oral-Wild Bird LD50: 562 mg/kg; Abdominal-Mouse LD50: 300 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxide fumes

Safety Information

Hazard category：

IRRITANT

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-22

safety instructions：

26-36-37/39

RTECS Number：

DJ0175000

Marks：

Storage features：

Warehouse ventilated, low temperature and dry

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H335

GHS Classification：

|Warning|H302 (91.11%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 45 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

highly toxic

4-Aminobenzophenone Use and Manufacturing

Uses

4-Aminobenzophenone, also known as p-aminobenzophenone, is an organic compound with the formula C₁₃H₁₁NO. The compound consists of a phenyl group and a phenyl ketone group, which are linked together by a nitrogen atom. 4-Aminobenzophenone usually appears in a yellowish solid form and has a characteristic aromatic odor. In the field of organic synthesis, 4-Aminobenzophenone often plays an important role as an intermediate in the synthesis of other compounds, especially in the synthesis of dyes and drugs. Due to its light absorption properties, the compound is used in photosensitive materials and photocurable coatings to help improve the performance of coatings. In the cosmetics industry, 4-Aminobenzophenone is used as a UV absorber to help protect the skin from UV damage and is often used in sunscreen products. In addition, the compound also has important applications in chemical research, especially when exploring new reaction paths and synthesis methods, and it provides scientists with valuable experimental materials.

Manufacturing Info：

Methanone, (4-aminophenyl)phenyl-: ACTIVE

Computed Properties

Molecular Weight:197.23
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:197.084063974
Monoisotopic Mass:197.084063974
Topological Polar Surface Area:43.1
Heavy Atom Count:15
Complexity:213
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 4-Aminobenzophenone

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4-Aminobenzophenone

CAS No.: 1137-41-3

Content: 99.00%

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