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Tramazoline

Tramazoline structure

Tramazoline 

structure
  • CAS No:

    1082-57-1

  • Formula:

    C13H17N3

  • Chemical Name:

    Tramazoline

  • Synonyms:

    1H-Imidazol-2-amine,4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-;2-Imidazoline,2-[(5,6,7,8-tetrahydro-1-naphthyl)amino]-;4,5-Dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine;Tramazoline;2-(5,6,7,8-Tetrahydro-1-naphthylamino)-2-imidazoline;Rhinol;Rhynaspray;Tobispray

Description

Tramazoline is a member of tetralins.|Tramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).

Tramazoline Basic Attributes

215.3

215.29

214-105-6

SLE31693IV

DTXSID5046936

R01AA09|R - Respiratory system

2934999090

Characteristics

36.4

1.77390

1.26

142.5 °C

353.0±52.0 °C(Predicted)

167.3ºC

1.673

3.7E-05mmHg at 25°C

Safety Information

P261, P264, P270, P271, P301+P312, P304+P312, P304+P340, P312, P330, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P301+P312, P304+P312, P304+P340, P312, P330, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline

Tramazoline Use and Manufacturing

Pharmaceuticals

Computed Properties

Molecular Weight:215.29
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:215.142247555
Monoisotopic Mass:215.142247555
Topological Polar Surface Area:36.4
Heavy Atom Count:16
Complexity:274
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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