Benzyloxycarbonyl-L-arginine
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Benzyloxycarbonyl-L-arginine
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CAS No:
1234-35-1
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Formula:
C14H20N4O4
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Chemical Name:
Benzyloxycarbonyl-L-arginine
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Synonyms:
L-Arginine,N2-[(phenylmethoxy)carbonyl]-;Arginine,N2-carboxy-,N2-benzyl ester,L-;Arginine,N2-carboxy-,N-benzyl ester;L-Arginine,N2-carboxy-,N-benzyl ester;N2-[(Phenylmethoxy)carbonyl]-L-arginine;Benzyloxycarbonyl-L-arginine;N2-Benzyloxycarbonyl-L-arginine;N-Carbobenzoxyarginine;Nα-(Benzyloxycarbonyl)arginine;(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-carbamimidamidopentanoic acid;(2S)-5-(Diaminomethylideneazaniumyl)-2-(phenylmethoxycarbonylamino)pentanoate;126298-72-4
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CAS No:
Characteristics
140
0.2
White to off white powder
1.1765 (rough estimate)
175 °C
448.73°C (rough estimate)
-10 ° (C=5.5, 0.2mol/L HCl)
2-8°C
-11 º (c=0.5, 0.5N HCl 24 ºC)
Safety Information
NONH for all modes of transport
3
20/21/22-36/37/38
24/25-36-26-S24/25
Xn
Stable under normal temperatures and pressures.
Benzyloxycarbonyl-L-arginine Use and Manufacturing
General procedure: To a solution of p-methoxyaniline (1b, 61.6 mg, 0.50 μmol)and cyanamide (25.2 mg, 0.60 μmol) in H2O (2.5 mL) wasadded Sc(OTf)3 (24.6 mg, 50 nmol) at r.t. After the solutionwas stirred at 100 °C for 2 d, the resulting mixture waswashed with CHCl3 (3 × 10 mL). The aqueous layer wasconcentrated in vacuo, and the residue was purified by filtering through silica gel pad (CHCl3–MeOH, 20:1).
Used in biochemical reagents and peptide synthesis.
L-Arginine, N2-[(phenylmethoxy)carbonyl]-: ACTIVE
Computed Properties
Molecular Weight:308.33
XLogP3:0.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:308.14845513
Monoisotopic Mass:308.14845513
Topological Polar Surface Area:140
Heavy Atom Count:22
Complexity:390
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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