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Methylprednisone

Methylprednisone structure

CAS No:
1247-42-3
Formula:
C22H28O5
Chemical Name:
Methylprednisone
Synonyms:
Pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16-methyl-,(16β)-;Pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16β-methyl-;(16β)-17,21-Dihydroxy-16-methylpregna-1,4-diene-3,11,20-trione;17,21-Dihydroxy-16β-methylpregna-1,4-diene-3,11,20-trione;Meprednisone;16β-Methylprednisone;Bitanisone;Deltacortene Beta;Betalone;Deltisona B;Betapred;Betapar;Betanisona;Lepicortin-Beta;Methylprednisone;Sch 4358;NSC 527579;Beta;42612-17-9
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

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Description

White Solid

Methylprednisone Basic Attributes

Molecular Weight：

372.45

Exact Mass：

372.45

EC Number：

214-996-1

NSC Number：

527579

HScode：

2937290000

Characteristics

PSA：

91.7

XLogP3：

2.06

Density：

1.28±0.1 g/cm3(Predicted)

Melting Point：

202.5 °C

Boiling Point：

574.4±50.0 °C(Predicted)

Flash Point：

315.2±26.6 °C

Refractive Index：

1.595

Storage Conditions：

Refrigerator

Specific rotation：

D +200° (dioxane)

Safety Information

Transport codes：

NONH for all modes of transport

Precautionary statement(s)：

P201, P202, P260, P264, P270, P281, P308+P313, P314, P405, P501

Hazard Statements：

H360

Drug Information

MeSH Entry Terms：

16-methylprednisone

Methylprednisone Use and Manufacturing

Uses

Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone. [1]The methylprednisone to MPL area under the curve ratio decreased from 0.19 +/- 0.04 in control to 0.14 +/- 0.03 in ketoconazole-treated rats (P less than .05) due to a

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:372.5
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:372.19367399
Monoisotopic Mass:372.19367399
Topological Polar Surface Area:91.7
Heavy Atom Count:27
Complexity:795
Undefined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Meprednisone

CAS No.: 1247-42-3

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