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Home > Encyclopedia > Tris(hydroxymethyl)aminomethane hydrochloride

Tris(hydroxymethyl)aminomethane hydrochloride

pharmaceutical raw materials
Tris(hydroxymethyl)aminomethane hydrochloride structure

Tris(hydroxymethyl)aminomethane hydrochloride 

structure
  • CAS No:

    1185-53-1

  • Formula:

    C4H11NO3.ClH

  • Chemical Name:

    Tris(hydroxymethyl)aminomethane hydrochloride

  • Synonyms:

    1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride (1:1);1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride;Tris chloride;Tris hydrochloride;Tris(hydroxymethyl)aminomethane hydrochloride;Tromethamine hydrochloride;Trizma hydrochloride;2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride;Tri(hydroxymethyl)aminomethane hydrochloride;T 6666;Tris-hydrochloric acid;Tris-HCl;35087-75-3;150551-82-9

  • Categories:

    Cosmetic Ingredient  >  Antimicrobials

Tris(hydroxymethyl)aminomethane hydrochloride Basic Attributes

157.59600

157.05100

214-684-5

383V75M34E

DTXSID4044373

2922199090

Characteristics

86.71000

-0.83690

white crystalline powder

1.05 g/mL at 20ºC

150.0-150.8 °C

357ºC at 760 mmHg

169.7ºC

H2O: soluble

Store at RT.

Safety Information

NONH for all modes of transport

3

R36/37/38

S26-S36

TY2900000

Xi

Stable. Incompatible with strong oxidizing agents, bases, moisture.

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (99.09%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 200 companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Tris(hydroxymethyl)aminomethane hydrochloride Use and Manufacturing

Uses

For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode;For Tris buffers, pH increases about 0.03 unit/掳C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.


Laboratory chemicals

Wholesale and retail trade|1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1): ACTIVE

Computed Properties

Molecular Weight:157.59
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:157.0505709
Monoisotopic Mass:157.0505709
Topological Polar Surface Area:86.7
Heavy Atom Count:9
Complexity:54
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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