Ferroceneacetic acid

To a 500 mL three-necked flask equipped with a mechanical stirrer and a spherical condenser were added 0.01 mol of acetyl ferrocene, 0.1 mol morpholine, 0.05 mol of sulfur and 0.001 mol of Na2S · 9H2O, Oil bath was heated to 128 deg C, Reflux 7h, TLC monitoring.The reaction is completed, The mixture was cooled to room temperature, Then, 10 mL of ethanol and 25 mL of 2 mol / L sodium hydroxide aqueous solution were added thereto, Stirring temperature, Reflux 4h, TLC monitoring.The reaction is completed, cool down, Adjust the pH value with hydrochloric acid to between 7 and 8, Filter cleaning, The filtrate was then adjusted to pH 1 with hydrochloric acid, Placed overnight, filter, Washed, A yellow-brown solid, Namely ferrocenyl acetic acid, The yield is 79percent.To a 500 mL three-necked flask equipped with a mechanical stirrer and a spherical condenser were added 0.01 mol of acetyl ferrocene, 0.1 mol morpholine, 0.05 mol of sulfur and 0.001 mol of Na2S · 9H2O, Oil bath was heated to 128 deg C, Reflux 7h, TLC monitoring.The reaction is completed, The mixture was cooled to room temperature, Then, 10 mL of ethanol and 25 mL of 2 mol / L sodium hydroxide aqueous solution were added thereto, Stirring temperature, Reflux 4h, TLC monitoring.The reaction is completed, cool down, Adjust the pH value with hydrochloric acid to between 7 and 8, Filter cleaning, The filtrate was then adjusted to pH 1 with hydrochloric acid, Placed overnight, filter, Washed, A yellow-brown solid, Namely ferrocenyl acetic acid, The yield is 79percent.