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Sporidesmin

Sporidesmin structure

Sporidesmin 

structure
  • CAS No:

    1456-55-9

  • Formula:

    C18H20ClN3O6S2

  • Chemical Name:

    Sporidesmin

  • Synonyms:

    3,11a-Epidithio-11aH-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-dione,9-chloro-2,3,5a,6,10b,11-hexahydro-10b,11-dihydroxy-7,8-dimethoxy-2,3,6-trimethyl-,(3R,5aR,10bS,11R,11aR)-;Sporidesmin;3,11a-Epidithio-11aH-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-dione,9-chloro-2,3,5a,6,10b,11-hexahydro-10b,11-dihydroxy-7,8-dimethoxy-2,3,6-trimethyl-,(3α,5aα,10bα,11β,11aα)-;(3R,5aR,10bS,11R,11aR)-9-Chloro-2,3,5a,6,10b,11-hexahydro-10b,11-dihydroxy-7,8-dimethoxy-2,3,6-trimethyl-3,11a-epidithio-11aH-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-dione;Sporidesmin A;Hydroxysporidesmin B;NSC 246152;1378-20-7;54868-51-8

Description

Sporidesmin A is an organic heteropentacyclic compound that has formula C18H20ClN3O6S2, produced by the saprophyte fungus Pithomyces chartarum. It is a mycotoxin responsible for the hepatogenous photosensitisation disease facial eczema in ruminants. It has a role as a mycotoxin and a Wnt signalling activator. It is an organic heteropentacyclic compound, an aromatic ether, an organochlorine compound, a secondary alcohol, a tertiary alcohol, a tertiary amino compound, an organic disulfide, a diketone and a cyclic ketone.

Sporidesmin Basic Attributes

473.943

473.95

H70LC3H0RW

Characteristics

153

0.2

179° (dependent on rate of heating)

D20 -45° (c = 0.98 in methanol)

Safety Information

6.1(b)

1544

Drug Information

isosporidesmin B

Computed Properties

Molecular Weight:474.0
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:2
Exact Mass:473.0482054
Monoisotopic Mass:473.0482054
Topological Polar Surface Area:153
Heavy Atom Count:30
Complexity:825
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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