1-(2-Phenylacetyl)-L-prolylglycine ethy ester
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1-(2-Phenylacetyl)-L-prolylglycine ethy ester
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CAS No:
157115-85-0
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Formula:
C17H22N2O4
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Chemical Name:
1-(2-Phenylacetyl)-L-prolylglycine ethy ester
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Synonyms:
Glycine,1-(2-phenylacetyl)-L-prolyl-,ethyl ester;Glycine,N-[1-(phenylacetyl)-L-prolyl]-,ethyl ester;Glycine,1-(phenylacetyl)-L-prolyl-,ethyl ester;1-(2-Phenylacetyl)-L-prolylglycine ethy ester;GVS 111;Noopept;SGS 111;Omberacetam;(S)-Ethyl 2-(1-(2-phenylacetyl)pyrrolidine-2-carboxamido)acetate
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CAS No:
Description
Noopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.IC50 Value:Target: in vitro: Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM) [1]. GVS-111 significantly increased
1-(2-Phenylacetyl)-L-prolylglycine ethy ester Basic Attributes
318.37
318.37
1592732-453-0
4QBJ98683M
DTXSID80166214
29339900
Characteristics
75.7
1.5
white powder
1.2±0.1 g/cm3
94.0 to 98.0 °C
547.3°C at 760 mmHg
284.8±30.1 °C
1.549
4.93E-12mmHg at 25°C
Drug Information
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)
ethyl phenylacetyl-Pro-Gly
Computed Properties
Molecular Weight:318.4
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:318.15795719
Monoisotopic Mass:318.15795719
Topological Polar Surface Area:75.7
Heavy Atom Count:23
Complexity:432
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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1-(2-Phenylacetyl)-L-prolylglycine ethy ester
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