High Quality 99% White Powder Nootropics Noopept CAS 157115-85-0 in ready stock

Noopept More Info

Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic nootropic compound developed in Russia, structurally related to the racetam family but significantly more potent. It is used primarily as a cognitive enhancer and neuroprotective agent.

Mechanism of Action

Noopept’s precise mechanism is not fully elucidated but involves several neurochemical pathways:
Neurotrophic factors: It increases the expression of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), which support neuroplasticity, neuronal survival, and long-term potentiation critical for memory and learning.
Modulation of neurotransmission: Noopept enhances acetylcholine signaling and modulates glutamate transmission, preventing excitotoxicity by reducing excessive glutamate release, thus protecting neurons from damage.
Hypoxia-inducible factor-1 (HIF-1) activation: Noopept increases the DNA-binding activity of HIF-1, a transcription factor involved in cellular adaptive responses to hypoxia, which may contribute to its neuroprotective effects.
Prodrug for cycloprolylglycine: Noopept is rapidly metabolized into cycloprolylglycine, an endogenous neuropeptide with nootropic properties, suggesting much of Noopept’s effects are mediated through this metabolite.
Brain wave modulation: It increases alpha and beta brain wave activity, promoting calmness, creativity, and improved cognitive flow states.

Applications

Cognitive enhancement: Improves memory formation, retention, recall, attention, and learning.
Neuroprotection: Protects neurons from oxidative stress, excitotoxicity, and apoptosis.
Potential therapeutic use in mild cognitive impairment, stroke recovery, and neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s) based on preclinical and limited clinical data.
Anxiolytic effects: May reduce anxiety and improve mood.

Pharmacokinetics

Rapidly absorbed orally with peak serum levels within minutes.
Noopept itself is quickly metabolized (within ~25 minutes) and is often undetectable in serum.
Metabolized into cycloprolylglycine and possibly phenylacetic acid; cycloprolylglycine levels increase in brain tissue after administration.
Shows slower elimination in humans compared to animals, with considerable individual variability.
Crosses the blood-brain barrier effectively.

Safety and Side Effects

Generally well tolerated with mild side effects.
Reported adverse effects include sleep disturbances, irritability, and increased blood pressure in some patients.
Limited clinical safety data; drug interactions are not well studied.
One small open-label trial in patients with mild cognitive disorders reported sleep issues (5/31), irritability (3/31), and elevated blood pressure (7/31).
No significant serious adverse effects reported in the limited human studies.

Package Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.