Azilsartan kamedoxomil
-
Azilsartan kamedoxomil
structure -
-
CAS No:
863031-24-7
-
Formula:
C30H24N4O8.K
-
Chemical Name:
Azilsartan kamedoxomil
-
Synonyms:
1H-Benzimidazole-7-carboxylic acid,1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester,potassium salt (1:1);1H-Benzimidazole-7-carboxylic acid,1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester,potassium salt;Azilsartan kamedoxomil;Azilsartan medoxomil monopotassium salt
- Categories:
-
CAS No:
Description
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. IC50 Value: 0.62 nM [2]Target: AT1 receptorin vitro: In aortic endothelial cells, azilsartan inhibited cell proliferation at concentrations as low as 1 μmol/l, whereas valsartan showed little or no antiproliferative effects at concentrations below 10 μmol/l. Antiproliferative effects of azilsartan were a
Azilsartan kamedoxomil is an organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension. It has a role as a prodrug, an antihypertensive agent and an angiotensin receptor antagonist. It contains an azilsartan medoxomil(1-).
Safety Information
|Warning|H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|P201, P202, P260, P263, P264, P270, P281, P308+P313, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Azilsartan kamedoxomil Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:606.6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:10
Exact Mass:606.11529519
Monoisotopic Mass:606.11529519
Topological Polar Surface Area:129
Heavy Atom Count:43
Complexity:1110
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Recommended Suppliers of Azilsartan kamedoxomil
-
![China]()
CN
YRS
Business licensedTrader Supplier of Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524,Milbemycin oxime,MeloxicamInquiryUnit Price: $100-130 /G FOBCAS No.: 863031-24-7Grade: Reagent GradeContent: 99% -
![China]()
CN
YRS
Business licensedTrader Supplier of Pharmaceutical intermediatesInquiryUnit Price: nullnull /null nullCAS No.: 863031-24-7Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
YRS
Business licensed Certified factoryManufactory Supplier of Manidipine Hydrochloride,Lercanidipine Hydrochloride 132866-11-6,Azilsartan Kamedoxomil 863031-24-7,Quetiapine Fumarate 111974-72-2,Manidipine Intermediates 841-77-0,Lercanidipine Intermediate 74936-72-4,Azilsartan Intermediate 91526-18-0,Finerenone intermediate 1050477-39-8,Lercanidipine Intermediate 65193-87-5,Finerenone intermediate 1050477-43-4,Finerenone intermediate 1050477-44-5InquiryCAS No.: 863031-24-7Grade: Pharmaceutical GradeContent: 99.0% -
![China]()
CN
YRS
Business licensed Certified factoryManufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic ChemicalsInquiryUnit Price: nullnull /null nullCAS No.: 863031-24-7Grade: Industrial GradeContent: 99% -
![China]()
CN
YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryUnit Price: nullnull /null nullCAS No.: 863031-24-7Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
Azilsartan
147403-03-0
-
Azilsartan medoxomil
863031-21-4
-
Azilsartan pharMaceutical interMediate
136304-78-4
-
2-Fluoro-4-trifluoromethyl-pyridine Formula
118078-66-3
-
Hydrolyzed vegetable protein Formula
100209-45-8
-
4-Fluoro-1,3-benzenediol Formula
103068-41-3
-
5-FLUORO-2-IODOPYRIDINE Structure
159870-80-1
-
2-FLUORO-6-IODOBENZOIC ACID Structure
111771-08-5
-
What is 2-FLUORO-3-METHOXYBENZOIC ACID
137654-20-7
-
What is 1-benzyl-4-methylpiperidin-3-one
32018-96-5