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Manufactory Supply: Azilsartan Kamedoxomil

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CAS No.:

863031-24-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Packaging:

5kg/drum, 10kg/drum, 20kg/drum, 25kg/drum

Sample Available:

Yes

Price valid (until):

2024-04-04

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Xuchang Hengsheng Pharmaceutical

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

120 days

Qualification:

Main Products:

Manidipine Hydrochloride,Lercanidipine Hydrochloride 132866-11-6,Azilsartan Kamedoxomil 863031-24-7,Quetiapine Fumarate 111974-72-2,Manidipine Intermediates 841-77-0,Lercanidipine Intermediate 74936-72-4

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Product Details
Seller Information

Description

Product Name: Azilsartan Kamedoxomil
Structural formula:

Molecular formula: C₃₀H₂₃KN₄O₈
Molecular weight: 606.63
Chemical Name: potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-2-aza-4-azanidacyclopent-2-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
CAS Number: 863031-24-7
Quality standards: Inhouse Standard

Assay: ≥99.0%

ECHEMI Editorial Reference

Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. IC50 Value: 0.62 nM [2]Target: AT1 receptorin vitro: In aortic endothelial cells, azilsartan inhibited cell proliferation at concentrations as low as 1 μmol/l, whereas valsartan showed little or no antiproliferative effects at concentrations below 10 μmol/l. Antiproliferative effects of azilsartan were a
Azilsartan kamedoxomil is an organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension. It has a role as a prodrug, an antihypertensive agent and an angiotensin receptor antagonist. It contains an azilsartan medoxomil(1-).

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Basic Info

Product Name:

Azilsartan kamedoxomil

Other Name:

1H-Benzimidazole-7-carboxylic acid,1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester,potassium salt (1:1);1H-Benzimidazole-7-carboxylic acid,1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester,potassium salt;Azilsartan kamedoxomil;Azilsartan medoxomil monopotassium salt

CAS No.:

863031-24-7

Molecular Formula:

C30H24N4O8.K

InChIKeys:

InChIKey=MIJNRHZSZJLCAG-UHFFFAOYSA-N

Molecular Weight:

606.6

Exact Mass:

606.115295

EC Number:

1308068-626-2

UNII:

WEC6I2K1FC

DSSTox ID:

DTXSID70235483

Categories:

Circulatory System Drugs

Characteristics

PSA:

155.59000

XLogP3:

4.70520

Appearance:

White or offwhite powder

Water Solubility:

Insoluble

See More Azilsartan kamedoxomil Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Azilsartan kamedoxomil Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Manidipine Hydrochloride,Lercanidipine Hydrochloride 132866-11-6,Azilsartan Kamedoxomil 863031-24-7,Quetiapine Fumarate 111974-72-2,Manidipine Intermediates 841-77-0,Lercanidipine Intermediate 74936-72-4

Location:
Jian an Fine Chemical Industrial Park, Xuchang City, Henan Province China

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
120 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
101-200

Year of Establishment:
2007

Company Certificates
- Pharmaceutical production license
Company Profile
Xuchang Hengsheng Pharmaceutical Co., Ltd. (Hengsheng) was built in January 2007. It is a technological enterprise specialized in the development, production and sale of pharmaceutical products which are APIs, Formulation and API intermediates.
Hengsheng is located at Zhangpan town in Xuchang, a city in the middle of Henan province. The site is near by Jing-Zhu Highway (Beijing- Zhuhai) and Jing-Guang Railway& High-Speed Railway (Beijing- Guangzhou), in the south of Zhengzhou and 40 km away from Zhengzhou Xinzheng International Airport. It is easy to arrive at the site.
Hengsheng is a developing modern manufacturing site with four synthesis workshops, one for drug synthesis workshop to manufacture APIs, the others for Formulation and API intermediates. The synthesis workshop of API manufacturing has passed China GMP check in Jan. 2018. All of other facilities is completed and meets the requirement of API manufacturing activities within this workshop.
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Manufactory Supply: Azilsartan Kamedoxomil

Product Details

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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