(2S,5R,6R)-3,3-DiMethyl-6-((R)-2-(3-(3-(Methylsulfonyl)-2-oxoiMidazolidine-1-carbonyl)ureido)-2-phenylacetaMido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodiuM salt

This product is a compound preparation, its components are mezlocillin sodium and sulbactam sodium.

When this product is used simultaneously with high-dose heparin and anticoagulants, coagulation parameters should be monitored. Probenecid can inhibit the renal excretion of this product. When using this product, the patient's non-enzymatic urine glucose reaction, urobilinogen test and urine protein determination may have false positive results. This product should be avoided in combination with drugs with strong acidity or alkalinity (below pH 4.0 or above pH 8.0).

The main ingredient of this product is mezlocillin sodium, and its chemical name is (2S, 5R, 6R)-3,3-dimethyl-6-[(R)-2[3-(methylsulfonyl)-2-oxo-1-imidazolidinecarboxamido]-2-phenylacetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]-heptane-2-carboxylic acid sodium salt.

1 Aspirin, indomethacin, phenylbutazone, and sulfonamides can reduce the excretion of this product in the renal tubules, thereby increasing the blood concentration of this product, prolonging the blood elimination half-life (t1/2), and the toxicity may also increase. 2 When this product is used in combination with allopurinol, the incidence of rash increases significantly, so the combination should be avoided. 3 This product should not be used in combination with acetaldehyde dehydrogenase inhibitors such as disulfiram. 4 When this product is used in combination with chloramphenicol for bacterial meningitis, the incidence of long-term sequelae is higher than when either is used alone. 5 This product can stimulate estrogen metabolism or reduce its enterohepatic circulation, thereby reducing the effectiveness of oral contraceptives. 6 Antibiotics such as chloramphenicol, erythromycin, tetracyclines and antibacterial drugs such as sulfonamides can interfere with the bactericidal activity of this product, so it is not suitable to be used in combination with this product, especially in the treatment of meningitis or severe cases that urgently need bactericidal drugs.

The main ingredient of this product is mezlocillin sodium, and its chemical name is (2S, 5R, 6R)-3,3-dimethyl-6-[(R)-2[3-(methylsulfonyl)-2-oxo-1-imidazolidinecarboxamido]-2-phenylacetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]-heptane-2-carboxylic acid sodium salt.

1 Aspirin, indomethacin, phenylbutazone, and sulfonamides can reduce the excretion of this product in the renal tubules, thereby increasing the blood concentration of this product, prolonging the blood elimination half-life (t1/2), and the toxicity may also increase. 2 When this product is used in combination with allopurinol, the incidence of rash increases significantly, so the combination should be avoided. 3 This product should not be used in combination with acetaldehyde dehydrogenase inhibitors such as disulfiram. 4 When this product is used in combination with chloramphenicol for bacterial meningitis, the incidence of long-term sequelae is higher than when either is used alone. 5 This product can stimulate estrogen metabolism or reduce its enterohepatic circulation, thereby reducing the effectiveness of oral contraceptives. 6 Antibiotics such as chloramphenicol, erythromycin, tetracyclines and antibacterial drugs such as sulfonamides can interfere with the bactericidal activity of this product, so it is not suitable to be used in combination with this product, especially in the treatment of meningitis or severe cases that urgently need bactericidal drugs.