Calcium hydroxide phosphate (Ca5(OH)(PO4)3)
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Calcium hydroxide phosphate (Ca5(OH)(PO4)3)
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CAS No:
12167-74-7
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Formula:
Ca.HO.O4P
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Chemical Name:
Calcium hydroxide phosphate (Ca5(OH)(PO4)3)
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Synonyms:
Calcium hydroxide phosphate (Ca5(OH)(PO4)3);Calcium phosphate (Ca10(OH)2(PO4)6);Calcium phosphate (Ca5OH(PO4)3);Calcium tribasic phosphate;Calcium hydroxyphosphate (Ca10(OH)2(PO4)6);Calcium hydroxide phosphate (Ca10(OH)2(PO4)6);Pentacalcium hydroxide triphosphate;Calcium phosphate hydroxide (Ca10(PO4)6(OH)2);Calcium phosphate hydroxide (Ca5(PO4)3(OH));Decacalcium hexaphosphate dihydroxide;Calcium hydroxyphosphate (Ca5(PO4)3OH);Pentacalcium hydroxylphosphate;Hydroxyapatite (synthetic);Calcium hydroxyapatite;Synthetic hydroxyapatite;1337-78-6;29796-40-5;205873-50-3;221359-86-0;947383-76-8;1398505-50-4;2172828-58-7;2376822-12-5;2608052-30-6;2639476-81-4
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CAS No:
Description
DryPowder; Liquid; OtherSolid; PelletsLargeCrystals
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
Calcium hydroxide phosphate (Ca5(OH)(PO4)3) Basic Attributes
502.31
501.67600
231-840-8
91D9GV0Z28
DTXSID50872537|DTXSID10872538
Hexagonal needles arranged in rosettes|Finely divided, crystalline, nonstoichiometric material.
3103900000
Characteristics
311.24000
0.98120
White aqueous suspension
3.14 g/cm3
1100 °C(lit.)
158ºC at 760 mmHg
Partially soluble in water.soluble in 1 M Hydrochloric acid.
2-8°C
Nonflammable
Decomposes above 1100 °C
Safety Information
NONH for all modes of transport
3
36/37/38
26-36-24/25-22
Xi
Warehouse ventilated, low temperature and dry
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Not Classified
Toxicity
Calcium hydroxyapatite deposition disease, or apatite gout, ... usually occurs in younger persons ...
A natural calcium phosphate (usually containing fluorine) occurring in earth's crust as phosphate rock. ... /Occurs in/ Eastern US, California, the former USSR, Canada, Europe. /Apatite/|The major constituent of bone & tooth material.
Drug Information
EXPT USE: WOMEN WITH PRIMARY BILIARY CIRRHOSIS MALABSORB CALCIUM, PHOSPHATE & VITAMIN D, & DEVELOP ACCELERATED CORTICAL BONE THINNING. HYDROXYAPATITE WAS ASSESSED FOR ITS VALUE IN THE TREATMENT OF CORTICAL BONE THINNING IN PRIMARY BILIARY CIRRHOSIS. CORTICAL BONE LOSS OCCURRED IN THE CONTROL GROUP. THE HYDROXYAPATITE GROUP SHOWED A SIGNIFICANT GAIN IN CORTICAL BONE THICKNESS.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. (See all compounds classified as Biocompatible Materials.)
Deposition of microcrystals such as ... calcium hydroxyapatite into joints can cause acute or chronic arthritis in a manner similar to that caused by monosodium urate deposition.
Alveograf
Calcium hydroxide phosphate (Ca5(OH)(PO4)3) Use and Manufacturing
Prepd from Ca(NO3)2 and KH2PO4; from calcium phosphate, dibasic; from Ca(NO3)2.4H2O and (NH4)3PO4 plus NH4OH.|Dense hydroxyapatite ceramics are made by compressing calcium phosphate solids from a very fine powder form, known as greenstate, into a pellet which is then subjected to a heat treatment that causes the powder particles to fuse together by means of solid-state diffusion.
Hydroxyapatite nanopowders, incorporated in biodegradable polymer composites1 or deposited on biocompatible substrates,2 have been shown to promote adhesions and proliferation of bone-forming (osteoblast) cells.
Agricultural chemicals (non-pesticidal)
Agricultural products (non-pesticidal)
10,000,000 - 50,000,000 lb
All other chemical product and preparation manufacturing|Hydroxylapatite (Ca5(OH)(PO4)3): ACTIVE|Apatite /is name which refers to/ a group of calcium phosphates having the type formula Ca10(X2)(PO4)6 where X is usually fluorine, chlorine, or hydroxyl group either singly or together. /Apatite/|... Rich in surface ions (carbonate, magnesium, citrate) which are readily replaced by fluoride ion, thus affording protection to teeth.|Calcium hydroxy-apatite or calcium hydroxy-phosphate, (Ca10(OH)2(PO4)6), may be formed to small extent in ammoniated superphosphate.
Cosmetics -> Abrasive; Bulking; Emulsion stabilizing
Computed Properties
Molecular Weight:502.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:13
Exact Mass:501.675955
Monoisotopic Mass:501.675955
Topological Polar Surface Area:260
Heavy Atom Count:21
Complexity:36.8
Covalently-Bonded Unit Count:9
Compound Is Canonicalized:Yes
Registered Holders
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INDIA PHOSPHATE AND ALLIED INDUSTRIES PRIVATE LTD
Active
United States
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INNOPHOS INC
Inactive
United States
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