Hydroxypropyl cellulose
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Hydroxypropyl cellulose
structure -
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CAS No:
9004-64-2
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Formula:
C3H8O2.xUnspecified
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Chemical Name:
Hydroxypropyl cellulose
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Synonyms:
Cellulose,2-hydroxypropyl ether;Hydroxypropyl cellulose;Hydroxypropyl ether of cellulose;Cellulose hydroxypropyl ether;Oxypropylated cellulose;Klucel;Hydroxypropyl cellulose ether;Klucel E;Klucel G;PM 50 (polymer);2-Hydroxypropyl cellulose;PM 50;Klucel H;Klucel GF;HPC-SL;Klucel MF;Klucel M;Klucel JF;Klucel J;Klucel LF;Klucel L;HPC-M;Klucel HF;Klucel EF;Hyprolose;HPC-L;LHPC 21;HPC-H;Nisso HPC;HPC;HPC-LR;O-(Hydroxypropyl)cellulose;Nisso HPC-SL;Nisso HPC-L;HPC-LG;O-(2-Hydroxypropyl)cellulose;Klucel HXF;Aqualon Klucel L;HPC-E;HPC-E (cellulose derivative);LH 31;HPC-MG;HPC-MF;JK 491;HPC-LE-G;HPC-S (cellulose derivative);HPC-EF-G;L-HPC;L-HPC-LH 31;L-HPC-LH 21;L-HPC-LH 41;L-HPC LH 11;G 4000HXL;L-HPC-LH 22;R 1000;R 1000 (cellulose derivative);HPC-S;HPC-SSL;LH 11;Klucel EXF;Lacrisert;LH 21;LH 32;LH 33;L-HPCLH 10;LH 20;LH 22;Nisso M;Nisso H;K 8913;K 9113;L-HPC 11;LHPC 20;E 463;LH-B 1;L-HPC 32W;AeroWhip 630;LH 20 (cellulose derivative);Klucel Nutra D;Celny L;Nisso HPC-SSL;Celny HPC-L;Celny HPC-SSL;Celny HPC-M;AeroWhip;AeroWhip 640;Celny H;L-HPC-LH-B 1;Nisso HPC-M;Nisso HPC-H;HPC-L 100M;Celny M;Celny SL;H 0386;H 0473;H 0474;H 0475;HPC-HF;L-HPC-NBD 022;Klucel ELF;Klucel M-CS;Lodicel LDC-H;Klucel HIND;NBD 020;NBD 22;NBD 021;Celny SSL;Celny SSL-SFP;HPC-SFP;HPC-SSL-SFP;HPC-L-FP;Klucel LF RM 822;NBD 022;Klucel HF Pharm;Klucel E 3042;WPQP 52000H;L-HPC NBD 020;Klucel MXF;HPC-EF;HPC-LL;ReCell HP 10;9076-24-8;65742-73-6;78214-41-2;150873-09-9;173523-78-9;192006-47-6;193561-69-2;210920-15-3;686343-47-5;927888-04-8;936102-79-3;1374408-53-3;1431958-25-6;1610923-54-0;2169285-63-4
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CAS No:
Description
White or yellowish-white powder or granules, hygroscopic after drying Hydroxypropyl cellulose is a white to slightly yellow-colored, odorless and tasteless powder.
Characteristics
0.00000
-1.24
White to light cream; powder
0.5g/mLat 25°C(lit.)
371.06 °C
891.2±65.0 °C at 760 mmHg
492.8±34.3 °C
1.532
soluble in polar organic solvents, in water at room temperature.soluble in water, methyl alcohol, ethyl alcohol and other organic solvents.
Hydroxypropyl cellulose powder is a stable material, although it is
hygroscopic after drying.
Aqueous solutions of hydroxypropyl cellulose are stable at pH
6.0–8.0, with the viscosity of solutions being relatively unaffected.
However, at low pH aqueous solutions may undergo acid
hydrolysis, resulting in chain scission and hence a decrease in
solution viscosity. The rate of hydrolysis increases with increasing
temperature and hydrogen ion concentration. At high pH, alkalicatalyzed
oxidation
Safety Information
NONH for all modes of transport
1
24/25
NF9050000
S24/S25
Stable. Incompatible with strong oxidizing agents. Combustible.
Hydroxypropyl cellulose Use and Manufacturing
Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility. It is used as an excipient, and topical ophthalmic protectant and lubricant.
Drug Function and Efficacy
This product can improve the blood supply to the vertebral basilar artery, regulate the function of the vestibular system, inhibit the vomiting center, and has anti-vertigo and antiemetic effects.
Registered Holders
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HUZHOU ZHANWANG PHARMACEUTICAL CO LTD
Active
United States
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AQUALON COMPANY
Active
United States
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Ashland Chemicals (Nanjing) Co., Ltd.
Active
China
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