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Hydroxypropyl cellulose

Hydroxypropyl cellulose structure

CAS No:
9004-64-2
Formula:
C3H8O2.xUnspecified
Chemical Name:
Hydroxypropyl cellulose
Synonyms:
Cellulose,2-hydroxypropyl ether;Hydroxypropyl cellulose;Hydroxypropyl ether of cellulose;Cellulose hydroxypropyl ether;Oxypropylated cellulose;Klucel;Hydroxypropyl cellulose ether;Klucel E;Klucel G;PM 50 (polymer);2-Hydroxypropyl cellulose;PM 50;Klucel H;Klucel GF;HPC-SL;Klucel MF;Klucel M;Klucel JF;Klucel J;Klucel LF;Klucel L;HPC-M;Klucel HF;Klucel EF;Hyprolose;HPC-L;LHPC 21;HPC-H;Nisso HPC;HPC;HPC-LR;O-(Hydroxypropyl)cellulose;Nisso HPC-SL;Nisso HPC-L;HPC-LG;O-(2-Hydroxypropyl)cellulose;Klucel HXF;Aqualon Klucel L;HPC-E;HPC-E (cellulose derivative);LH 31;HPC-MG;HPC-MF;JK 491;HPC-LE-G;HPC-S (cellulose derivative);HPC-EF-G;L-HPC;L-HPC-LH 31;L-HPC-LH 21;L-HPC-LH 41;L-HPC LH 11;G 4000HXL;L-HPC-LH 22;R 1000;R 1000 (cellulose derivative);HPC-S;HPC-SSL;LH 11;Klucel EXF;Lacrisert;LH 21;LH 32;LH 33;L-HPCLH 10;LH 20;LH 22;Nisso M;Nisso H;K 8913;K 9113;L-HPC 11;LHPC 20;E 463;LH-B 1;L-HPC 32W;AeroWhip 630;LH 20 (cellulose derivative);Klucel Nutra D;Celny L;Nisso HPC-SSL;Celny HPC-L;Celny HPC-SSL;Celny HPC-M;AeroWhip;AeroWhip 640;Celny H;L-HPC-LH-B 1;Nisso HPC-M;Nisso HPC-H;HPC-L 100M;Celny M;Celny SL;H 0386;H 0473;H 0474;H 0475;HPC-HF;L-HPC-NBD 022;Klucel ELF;Klucel M-CS;Lodicel LDC-H;Klucel HIND;NBD 020;NBD 22;NBD 021;Celny SSL;Celny SSL-SFP;HPC-SFP;HPC-SSL-SFP;HPC-L-FP;Klucel LF RM 822;NBD 022;Klucel HF Pharm;Klucel E 3042;WPQP 52000H;L-HPC NBD 020;Klucel MXF;HPC-EF;HPC-LL;ReCell HP 10;9076-24-8;65742-73-6;78214-41-2;150873-09-9;173523-78-9;192006-47-6;193561-69-2;210920-15-3;686343-47-5;927888-04-8;936102-79-3;1374408-53-3;1431958-25-6;1610923-54-0;2169285-63-4
Categories:
Cosmetic Ingredient > Film Forming

Description

White or yellowish-white powder or granules, hygroscopic after drying Hydroxypropyl cellulose is a white to slightly yellow-colored, odorless and tasteless powder.

Hydroxypropyl cellulose Basic Attributes

Molecular Weight：

59.08708

Exact Mass：

806.451111

HScode：

39129000

Characteristics

PSA：

0.00000

XLogP3：

-1.24

Appearance：

White to light cream; powder

Density：

0.5g/mLat 25°C(lit.)

Melting Point：

371.06 °C

Boiling Point：

891.2±65.0 °C at 760 mmHg

Flash Point：

492.8±34.3 °C

Refractive Index：

1.532

Water Solubility：

soluble in polar organic solvents, in water at room temperature.soluble in water, methyl alcohol, ethyl alcohol and other organic solvents.

Storage Conditions：

Hydroxypropyl cellulose powder is a stable material, although it is hygroscopic after drying.
Aqueous solutions of hydroxypropyl cellulose are stable at pH 6.0–8.0, with the viscosity of solutions being relatively unaffected. However, at low pH aqueous solutions may undergo acid hydrolysis, resulting in chain scission and hence a decrease in solution viscosity. The rate of hydrolysis increases with increasing temperature and hydrogen ion concentration. At high pH, alkalicatalyzed oxidation

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

24/25

RTECS Number：

NF9050000

Marks：

S24/S25

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents. Combustible.

Hydroxypropyl cellulose Use and Manufacturing

Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility. It is used as an excipient, and topical ophthalmic protectant and lubricant.

Material

Sodium hydroxide

Propylene Oxide

Hydrochloric acid

Drug Function and Efficacy

This product can improve the blood supply to the vertebral basilar artery, regulate the function of the vestibular system, inhibit the vomiting center, and has anti-vertigo and antiemetic effects.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Difenidol Hydrochloride Tablets
Ingredients	Each tablet of this product contains 25 mg of difenidol hydrochloride, and the excipients are starch, sucrose, magnesium stearate, microcrystalline cellulose, and hydroxypropyl cellulose.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	25mg
Manufacturer	Beijing Haiwang Zhongxin Pharmaceutical Co., Ltd.

Oyster calcium carbonate tablets
Ingredients	Each tablet of this product contains 25 mg of calcium. Excipients are: starch, hydroxypropyl cellulose, magnesium stearate.
Indication	1. This product should not be used in combination with digitalis drugs. 2. Drinking a lot of alcoholic and caffeinated beverages and smoking a lot will inhibit the absorption of calcium. 3. Eating a lot of fiber-rich foods can inhibit calcium absorption, because calcium combines with cellulose to form compounds that are not easily absorbed. 4. This product is used with phenytoin sodium and tetracyclines, and the absorption of both is reduced. 5. Vitamin D, contraceptives, and estrogen can increase calcium absorption. 6. When aluminum-containing antacids are taken with this product, aluminum absorption increases. 7. When this product is used in combination with thiazide diuretics, hypercalcemia is likely to occur (due to increased renal tubular calcium reabsorption). 8. When this product is used in combination with potassium-containing drugs, attention should be paid to the occurrence of arrhythmias. 9. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Specifications	As Ca 25mg
Manufacturer	Guangzhou Baiyunshan Guanghua Pharmaceutical Co., Ltd.

Difenidol Hydrochloride Tablets
Ingredients	Each tablet of this product contains 25 mg of difenidol hydrochloride, and the excipients are starch, sucrose, magnesium stearate, microcrystalline cellulose, and hydroxypropyl cellulose.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	25mg

See More Related Drugs

Registered Holders

HUZHOU ZHANWANG PHARMACEUTICAL CO LTD

United States
Active
AQUALON COMPANY

United States
Active
Ashland Chemicals (Nanjing) Co., Ltd.

China
Active

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56508-80-6
CELLULOSE TRIBENZOATE

37361-36-7
Sodium cellulose sulfate

9005-22-5
Hydroxypropyl methyl cellulose phthalate Formula

9050-31-1
Calcium carboxymethyl cellulose Formula

9050-04-8
Carboxymethyl Cellulose Formula

9000-11-7
Hydroxybutyl methyl cellulose Structure

9041-56-9
Ethyl hydroxyethyl cellulose Structure

9004-58-4
What is Hydroxypropyl acrylate polymer

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Guide of Hydroxypropyl cellulose

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Material
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

Hydroxypropyl cellulose

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