Propanoic acid, 2-hydroxy-, iron(2+) salt (2:1)

233.99

233.982674

227-608-0

121

-1.25310

Greenish-white crystals or light green powder having a characteristic smell

227.6ºC at 760 mmHg

109.9ºC

Soluble in water. Practically insoluble in ethanol

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

LD50 orally in mice: 147 ±30 mg/kg (Eickholt, White)

Between 4 and 6 (2 % solution)

MP: DECOMPOSES; 2.1 G SOL IN 100 CC WATER AT 10 °C, 8.5 G SOL IN 100 CC WATER AT 100 °C, INSOL IN ETHER /TRIHYDRATE/|Deliquescent; affected by light; combustible /Trihydrate/|Standard molar enthalpy (heat) of formation at 298.15 deg K is -272.0 kJ/mol (crystal)|Molar enthalpy (heat) of fusion 24 kJ/mol at 1377 °C|Sugar, glycerin, & many organic hydroxy acids hinder precipitation. In neutral solution, soluble carbonates, phosphates, & oxalates produce precipitation. /Ferrous salts/

2

OD5525000

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Certification of this color additive when used for coloring ripe olives is not necessary for the protection of the public health, and therefore batches thereof are exempt from the certification pursuant to section 721(c) of the act.|Substance added directly to human food affirmed as generally recognized as safe (GRAS).|Ferrous lactate used as a nutrient and/or dietary supplement in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

|Warning|H302 (97.54%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 987 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|All ... /iron/ preparations should be kept in child-proof bottles. /Iron preparations/

If inhaled, iron is a local irritant to the lung and gastrointestinal tract. /Iron compounds/

LD50 Mouse oral 137 +/- 30 mg/kg|LD50 Rabbit sc 578 mg/kg /Trihydrate/|LD50 Rabbit iv 287 mg/kg /Trihydrate/|LD50 Mouse oral 147 mg/kg

...There is concern that the individual with metabolic defects that impair the ability to regulate iron absorption will be at risk from excessive exposure to iron, primarily as a result of acceleration of accumulation of iron in the body and an earlier onset of clinical symptoms of the disease. /Iron salts/

MEDICATION (VET): In iron deficiency pig anemias.|MEDICATION (VET): Hematinic

Gastrointestinal absorption of iron is adequate and essentially equal from...ferrous...sulfate, fumarate, gluconate, succinate, glutamate, and lactate.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. /Iron and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Iron and related compounds/|Maintain an open airway and assist ventilation if necessary. Treat shock caused by hemorrhagic gastrointestinitis aggressively with intravenous crystalloid fluids, and replace blood if needed. Patients are often markedly hypovolemic owing to gastrointestinal losses and third spacing of fluids into the intestinal wall and interstitial space. Treat coma, seizures, and metabolic acidosis if they occur. For seriously intoxicated victims (eg, shock, severe acidosis, and/or serum iron > 500-600 mcg/dL) administer deferoxamine. Monitor the urine for the urine for the characteristic orange or pink deferoxamine-iron complex. Therapy may be stopped when the urine returns to normal or when the serum iron level decreases to the normal range. Prolonged deferoxamine has been associated with adult respiratory distress syndrome and Yersinia sepsis.|Activated charcoal is not effective. Ipecac is not recommended, because it can aggravate iron-induced gastrointestinal irritation and interfere with whole bowel irrigation. Consider gastric lavage if product was a liquid formulation or tablets were chewed. Do-not use phosphate-containing solutions for lavage; these may result in life-threatening hypernatremia, hyperphosphatemia, and hypocalcemia. Bicarbonate and deferoxamine lavage are of doubtful efficacy. Deferoxamine lavage is not effective and may enhance iron absorption. Whole-bowel irrigation is very effective for ingested tablets and may be considered first-line treatment, especially if large numbers of tablets are visible on plain abdominal x-ray. Massive ingestions may lead to concretions or bezoars. Repeated or prolonged whole-bowel irrigation may remove tablets. Endoscopy or surgical gastrotomy is rarely required.|Hemodialysis and hemoperfusion are not effective for removing iron but may be necessary to remove iron-deferoxamine complex in patients with renal failure. Exchange transfusion is occasionally used for massive pediatric ingestions but is of questionable efficacy.

2-hydroxypropanoic acid, iron(2+) salt

Contains approx 24% iron. ... a commercial product, "jernox" pellets, containing approx equal parts of the lactate & sulfate, is avail for sprinkling on the piglet pen floor.

Food additives -> Flavoring Agents|Food Additives -> COLOUR_RETENTION_AGENT; NUTRIENT_SUPPLEMENT; -> JECFA Functional Classes

Flavoring Agents|Food Additives -> COLOUR_RETENTION_AGENT; NUTRIENT_SUPPLEMENT;