(-)-Xanthatin
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(-)-Xanthatin
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CAS No:
26791-73-1
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Formula:
C15H18O3
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Chemical Name:
(-)-Xanthatin
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Synonyms:
2H-Cyclohepta[b]furan-2-one,3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-[(1E)-3-oxo-1-buten-1-yl]-,(3aR,7S,8aS)-;2H-Cyclohepta[b]furan-2-one,3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-(3-oxo-1-butenyl)-,[3aR-(3aα,7β,8aβ)]-;Xanthatin;3-Cycloheptene-1-acetic acid,7-hydroxy-5-methyl-α-methylene-4-(3-oxo-1-butenyl)-,γ-lactone;2H-Cyclohepta[b]furan-2-one,3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-[(1E)-3-oxo-1-butenyl]-,(3aR,7S,8aS)-;(3aR,7S,8aS)-3,3a,4,7,8,8a-Hexahydro-7-methyl-3-methylene-6-[(1E)-3-oxo-1-buten-1-yl]-2H-cyclohepta[b]furan-2-one;(-)-Xanthatin;87-14-9;21959-65-9;160549-24-6
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CAS No:
Description
Xanthatin is isolated from Xanthium strumarium leaves. Xanthatin exhibits strong antitumor activities against a variety of cancer cells through apoptosis persuasion and shows anti-inflammatory activities by inhibiting PGE2 synthesis and 5-lipoxygenase activity[1]. Xanthatin is a potent and orally active inhibitor of VEGFR2 kinase activity with an IC50 of 3.8 μM and prominently blocks the phosphorylation of VEGFR2 at Tyr951 site. Xanthatin inhibits angiogenesis and has the potential for t
Characteristics
43.37000
1.58
1.1±0.1 g/cm3
111-112 °C
444.3±45.0 °C at 760 mmHg
199.1±28.8 °C
1.528
4.33E-08mmHg at 25°C
D30 -20° (ethanol)
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