Creosote
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Creosote
structure -
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CAS No:
8001-58-9
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Chemical Name:
Creosote
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Synonyms:
Creosote;Coal creosote;Creosote,coal tar;Coal tar creosote;Sakresote 100
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CAS No:
Description
Creosote is an oily liquid with a burning taste,obtained by distilling coal and woodtar, used as an antiseptic and wood preservative. Creosote oil is a yellow-to-green oily liquid that boils between 240 and 270 °C, is immiscible with water and soluble in alcohol,and is derived by the fractional distillation of coal tar, used as a wood preservative, fungicide and disinfectant. Also, coal-tar creosote. The term “coal tar products,” as used by NIOSH, includes coal tar and two of the fractionatio
BLACK-TO-BROWN OILY LIQUID WITH CHARACTERISTIC ODOUR.
Creosote Basic Attributes
136.11
136.027277375
232-287-5
0572
1993
DTXSID2023987|DTXSID00570177
R - Respiratory system
27079100
Characteristics
1.07-1.08 g/cm3
20 °C (approx)
194-400 °C
>66 °C c.c.
Solubility in water: very poor
Vapor pressure, kPa at 20 °C: ~ 6
LD50 oral in rat: 725mg/kg
335 °C
Safety Information
6.1(b)
UN 2922 8/PG 2
3
23/24/25-34-48/20/21/22-68-45
26-36/37/39-45-53
GO5870000
T,C
Combustible.|Carcinogens, Flammable - 2nd degree
|Danger|H315 (90.91%): Causes skin irritation [Warning Skin corrosion/irritation]|P201, P202, P261, P264, P272, P273, P280, P281, P302+P352, P305+P351+P338, P308+P313, P321, P332+P313, P333+P313, P337+P313, P362, P363, P391, P405, and P501|Aggregated GHS information provided by 11 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H315: Causes skin irritation [Warning Skin corrosion/irritation]|P201, P202, P260, P261, P264, P271, P272, P280, P281, P284, P302+P352, P304+P340, P308+P313, P310, P320, P321, P332+P313, P333+P313, P362, P363, P403+P233, P405, and P501|H227: Combustible liquid [Warning Flammable liquids]|P201, P202, P210, P260, P261, P264, P270, P271, P272, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P370+P378, P403+P233, P403+P235, P405, and P501
Use water spray, powder, foam, carbon dioxide.
Personal protection: complete protective clothing, face shield and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in covered containers as far as possible.
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs.
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C , especially on spraying.
The substance is irritating to the eyes, skin and respiratory tract. Exposure to sun may enhance the irritating effect of this substance. This may result in burns. Ingestion could cause death. Medical observation is indicated.
Repeated or prolonged contact with skin may cause dermatitis and hyperpigmentation of skin. This substance is probably carcinogenic to humans.
NO open flames.
AVOID ALL CONTACT!
Use local exhaust or breathing protection.
Protective gloves. Protective clothing.
Wear safety goggles or eye protection in combination with breathing protection.
Drug Information
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.
Cough. Shortness of breath.
MAY BE ABSORBED! Redness. Burning sensation.
Redness. Pain.
Creosote Use and Manufacturing
Wood preservative, disinfectant, insecticide.
Creosote: ACTIVE
Fire Hazards -> Carcinogens, Flammable - 2nd degree
Computed Properties
Molecular Weight:136.11
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:136.027277375
Monoisotopic Mass:136.027277375
Topological Polar Surface Area:54.6
Heavy Atom Count:10
Complexity:190
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It can inhibit the excessive secretion of intestinal fluid, promote the absorption of intestinal fluid, reduce the amount of water in the intestine, thereby reducing the water content of the stool, that is, preventing diarrhea. It can inhibit intestinal peristalsis, thus preventing diarrhea caused by hypermotility of the intestine. It can effectively inhibit the Vero toxin produced by O157 Escherichia coli and the damage to intestinal mucosal epithelial cells caused by it.
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