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L-Lactic acid

L-Lactic acid structure

CAS No:
79-33-4
Formula:
C3H6O3
Chemical Name:
L-Lactic acid
Synonyms:
Propanoic acid,2-hydroxy-,(2S)-;Lactic acid,L-;Propanoic acid,2-hydroxy-,(S)-;(2S)-2-Hydroxypropanoic acid;d-Lactic acid;Paralactic acid;Sarcolactic acid;(S)-(+)-Lactic acid;(+)-Lactic acid;L-Lactic acid;(S)-Lactic acid;L-(+)-α-Hydroxypropionic acid;Espiritin;Tisulac;(S)-2-Hydroxypropionic acid;L-(+)-Lactic acid;(S)-2-Hydroxypropanoic acid;PH 90;PURAC;PURAC Powder H 60;HiPure 90;(2S)-2-Hydroxypropanoic acid;Purac FCC 50;Purac Sanilac;1715-99-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

Liquid

(S)-lactic acid is an optically active form of lactic acid having (S)-configuration. It has a role as an Escherichia coli metabolite and a human metabolite. It is a 2-hydroxypropanoic acid and a (2S)-2-hydroxy monocarboxylic acid. It is a conjugate acid of a (S)-lactate. It is an enantiomer of a (R)-lactic acid.|Lactic Acid, L- is the levorotatory isomer of lactic acid, the biologically active isoform in humans. Lactic acid or lactate is produced during fermentation from pyruvate by lactate dehydrogenase. This reaction, in addition to producing lactic acid, also produces nicotinamide adenine dinucleotide (NAD) that is then used in glycolysis to produce energy source adenosine triphosphate (ATP).|A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)

L-Lactic acid Basic Attributes

Molecular Weight：

90.08

Exact Mass：

90.08

BRN：

1720251

EC Number：

201-196-2

UNII：

F9S9FFU82N

DSSTox ID：

DTXSID6034689

NCI Thesaurus Code：

C61808

HScode：

29181100

Characteristics

PSA：

57.5

XLogP3：

-0.7

Appearance：

White Powder/Solid

Density：

1.3±0.1 g/cm3

Melting Point：

53 °C

Boiling Point：

125 °C

Flash Point：

>230 °F

Refractive Index：

1.451

Water Solubility：

H2O: 10 mg/mL, clear, colorless

Storage Conditions：

2-8°C

Toxicity：

LD50 intraperitoneal in mouse: 3194mg/kg

Specific rotation：

-13.5 º (c=2.5, 1.5N NaOH)

Safety Information

Packing level：

III

Hazard category：

Transport codes：

3261

wgk germany：

hazard class code：

38-41-34-36/37/38-36-35

safety instructions：

26-39-45-36/37/39-36

RTECS Number：

OD2800000

Marks：

Xi,C

Precautionary statement(s)：

P280-P305 + P351 + P338-P310

Hazard Statements：

H314

GHS Classification：

|Danger|H314 (18.87%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P332+P313, P362, P363, P405, and P501|Aggregated GHS information provided by 1172 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501

Drug Information

Drug Indication：

Prevention of pregnancy

MeSH Entry Terms：

2 Hydroxypropanoic Acid

L-Lactic acid Use and Manufacturing

Uses

Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o

Pigments

Cleaning and furnishing care products

Production

1,000,000 - 10,000,000 lb

Manufacturing Info：

All other chemical product and preparation manufacturing|Propanoic acid, 2-hydroxy-, (2S)-: ACTIVE

Use Classification：

EPA Safer Chemical Functional Use Classes -> Antimicrobial Actives;Chelating Agents;Preservatives and Antioxidants;Processing Aids and Additives|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:90.08
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:90.031694049
Monoisotopic Mass:90.031694049
Topological Polar Surface Area:57.5
Heavy Atom Count:6
Complexity:59.1
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of L-Lactic acid

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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L-Lactic acid

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