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Home > Encyclopedia > L-Lactic acid

L-Lactic acid

pharmaceutical raw materials
L-Lactic acid structure

L-Lactic acid 

structure
  • CAS No:

    79-33-4

  • Formula:

    C3H6O3

  • Chemical Name:

    L-Lactic acid

  • Synonyms:

    Propanoic acid,2-hydroxy-,(2S)-;Lactic acid,L-;Propanoic acid,2-hydroxy-,(S)-;(2S)-2-Hydroxypropanoic acid;d-Lactic acid;Paralactic acid;Sarcolactic acid;(S)-(+)-Lactic acid;(+)-Lactic acid;L-Lactic acid;(S)-Lactic acid;L-(+)-α-Hydroxypropionic acid;Espiritin;Tisulac;(S)-2-Hydroxypropionic acid;L-(+)-Lactic acid;(S)-2-Hydroxypropanoic acid;PH 90;PURAC;PURAC Powder H 60;HiPure 90;(2S)-2-Hydroxypropanoic acid;Purac FCC 50;Purac Sanilac;1715-99-7

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.


Liquid


(S)-lactic acid is an optically active form of lactic acid having (S)-configuration. It has a role as an Escherichia coli metabolite and a human metabolite. It is a 2-hydroxypropanoic acid and a (2S)-2-hydroxy monocarboxylic acid. It is a conjugate acid of a (S)-lactate. It is an enantiomer of a (R)-lactic acid.|Lactic Acid, L- is the levorotatory isomer of lactic acid, the biologically active isoform in humans. Lactic acid or lactate is produced during fermentation from pyruvate by lactate dehydrogenase. This reaction, in addition to producing lactic acid, also produces nicotinamide adenine dinucleotide (NAD) that is then used in glycolysis to produce energy source adenosine triphosphate (ATP).|A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)

L-Lactic acid Basic Attributes

90.08

90.08

1720251

201-196-2

F9S9FFU82N

DTXSID6034689

C61808

29181100

Characteristics

57.5

-0.7

White Powder/Solid

1.3±0.1 g/cm3

53 °C

125 °C

>230 °F

1.451

H2O: 10 mg/mL, clear, colorless

2-8°C

LD50 intraperitoneal in mouse: 3194mg/kg

-13.5 º (c=2.5, 1.5N NaOH)

Safety Information

III

8

3261

1

38-41-34-36/37/38-36-35

26-39-45-36/37/39-36

OD2800000

Xi,C

P280-P305 + P351 + P338-P310

H314

|Danger|H314 (18.87%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P332+P313, P362, P363, P405, and P501|Aggregated GHS information provided by 1172 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501

Drug Information

Prevention of pregnancy

2 Hydroxypropanoic Acid

L-Lactic acid Use and Manufacturing

Uses

Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o


Pigments


Cleaning and furnishing care products

Production

1,000,000 - 10,000,000 lb

All other chemical product and preparation manufacturing|Propanoic acid, 2-hydroxy-, (2S)-: ACTIVE

EPA Safer Chemical Functional Use Classes -> Antimicrobial Actives;Chelating Agents;Preservatives and Antioxidants;Processing Aids and Additives|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:90.08
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:90.031694049
Monoisotopic Mass:90.031694049
Topological Polar Surface Area:57.5
Heavy Atom Count:6
Complexity:59.1
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Lactic acid from muscle tissue; may play a role in energy metabolism and regulation of muscular function.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • PURAC BIOQUIMICA SAU

    United States United States
    Active
  • Purac Bioquimica S.A.

    European Union European Union
    Active
  • R&G PharmaStudies Co., Ltd.

    China China
    Inactive

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