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Valnemulin hydrochloride

Valnemulin hydrochloride structure

CAS No:
133868-46-9
Formula:
C31H52N2O5S^.HCl
Chemical Name:
Valnemulin hydrochloride
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Valnemulin hydrochloride is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit.

Valnemulin hydrochloride Basic Attributes

Molecular Weight：

601.28

Exact Mass：

600.336365

EC Number：

1308068-626-2

DSSTox ID：

DTXSID30158407

Characteristics

PSA：

144

XLogP3：

6.39740

Boiling Point：

672.7ºC at 760 mmHg

Flash Point：

360.6ºC

Storage Conditions：

0-6°C

Safety Information

Packing level：

Ⅲ

Transport codes：

3077

hazard class code：

Precautionary statement(s)：

P261, P264, P270, P271, P273, P280, P301+P312, P304+P340, P305+P351+P338, P312, P330, P337+P313, P391, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P273, P280, P301+P312, P304+P340, P305+P351+P338, P312, P314, P330, P337+P313, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 6 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Valnemulin hydrochloride Use and Manufacturing

Valnemulin hydrochloride is the salt prepared from valnemulin taking advantage of the basic amino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals, and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.

Computed Properties

Molecular Weight:601.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:10
Exact Mass:600.3363717
Monoisotopic Mass:600.3363717
Topological Polar Surface Area:144
Heavy Atom Count:40
Complexity:969
Undefined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Valnemulin hydrochloride

HNB Biotech Contact Supplier

CN
1 YR

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Veterinary Valnemulin Hydrochloride Powder CAS 133868-46-9 Valnemulin HCl

CAS No.: 133868-46-9

Grade: USP / EP / BP / JP Grade

Content: 99%

Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Veterinary Valnemulin Hydrochloride CAS 133868-46-9 Valnemulin HCl

CAS No.: 133868-46-9

Grade: Pharmaceutical Grade

Content: 99%

Inquiry