Geniposidic acid
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Geniposidic acid
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CAS No:
27741-01-1
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Formula:
C16H22O10
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Chemical Name:
Geniposidic acid
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Synonyms:
Cyclopenta[c]pyran-4-carboxylic acid,1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-,(1S,4aS,7aS)-;Cyclopenta[c]pyran-4-carboxylic acid,1α-(β-D-glucopyranosyloxy)-1,4aα,5,7aα-tetrahydro-7-(hydroxymethyl)-;Cyclopenta[c]pyran-4-carboxylic acid,1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-,[1S-(1α,4aα,7aα)]-;(1S,4aS,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid;Geniposidic acid;27932-72-5
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CAS No:
Description
Geniposidic acid is an effective anticancer and radioprotection agent.Target: OthersMice were given an intraperitoneal injection of Geniposidic acid (GA) (12.5, 25, 50 mg/kg) 1 h before receiving GA against d-galactosamine (GalN) (800 mg/kg)/LPS (40 μg/kg). Liver and blood samples were collected 1 and 8 h after GalN/LPS injection. The survival rate of the GA group was significantly higher than the control. GalN/LPS increased serum aminotransferase activity, serum tumor necrosis factor-α
Geniposidic acid is a terpene glycoside.
Characteristics
166
-2.7
1.6±0.1 g/cm3
138-140 °C @ Solvent: Methanol
684.1ºC at 760 mmHg
250.9±25.0 °C
1.660
Geniposidic acid Use and Manufacturing
Geniposidic acid is an effective anticancer and radioprotection agent. Geniposidic acid might be a more potent tumor growth inhibitor than geniposide (GP) when combined with the X-irradiation, though there was no significant synergetic effect on their com
Computed Properties
Molecular Weight:374.34
XLogP3:-2.7
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:5
Exact Mass:374.12129689
Monoisotopic Mass:374.12129689
Topological Polar Surface Area:166
Heavy Atom Count:26
Complexity:602
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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