Propylene glycol dinitrate Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | Propane-1,2-diyl dinitrate |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | 1,2-dinitrooxy-propane; PGDN; 1,2-Propanediol,dinitrate |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Industrial and scientific research uses. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
no data available
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | no data available |
|---|---|
| Signal word | no data available |
| Hazard statement(s) | no data available |
| Precautionary statement(s) | |
| Prevention | no data available |
| Response | no data available |
| Storage | no data available |
| Disposal | no data available |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| Propane-1,2-diyl dinitrate | Propane-1,2-diyl dinitrate | 6423-43-4 | 229-180-0 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Irritation eyes; conjunctivitis; methemoglobinemia; headache, impaired balance, visual disturbance Target Organs: Eyes, central nervous system, blood, liver, kidneys (NIOSH, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Maintain an open airway and assist ventilation if necessary. administer supplemental oxygen. Treat hypotension with supine positioning, crystalloid intravenous fluids, and low-dose pressors if needed. Monitor vital signs and ECG for 4-6 hours. Symptomatic methemoglobinemia may be treated with methylene blue. Administer activated charcoal if available. Nitrates and Nitrites
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
To Fight fire use/ powder, water spray, foam, carbon dioxide.
5.2 Specific hazards arising from the chemical
Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion. Explosive.
5.3 Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Evacuate danger area! Consult an expert! Remove all ignition sources. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus.)
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames, NO sparks and NO smoking. Do NOT expose to friction or shock. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Fireproof.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 0.05 ppm as TWA; (skin); BEI issued.MAK: 0.069 mg/m3, 0.01 ppm; peak limitation category: II(1); skin absorption (H); pregnancy risk group: C
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear face shield or eye protection in combination with breathing protection.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use ventilation, local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | Propylene glycol dinitrate is a colorless liquid with a disagreeable odor. Mp: -30°C. Density 1.37 g/cm3 at 20°C. Slightly soluble in water (7.97 g/L H2O at 24.85°C). |
|---|---|
| Colour | Red-orange liquid |
| Odour | no data available |
| Melting point/freezing point | 18° F (NIOSH, 2016) |
| Boiling point or initial boiling point and boiling range | 206.7ºC at 760 mmHg |
| Flammability | Combustible Liquid |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 98.5ºC |
| Auto-ignition temperature | no data available |
| Decomposition temperature | 121°C |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | 0.1 % (NIOSH, 2016) |
| Partition coefficient n-octanol/water | log Kow = 1.59 /Estimated/ |
| Vapour pressure | 0.07 mm Hg at 72° F (NIOSH, 2016) |
| Density and/or relative density | 1.423g/cm3 |
| Relative vapour density | (air = 1): 5.73 |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Heating may cause violent combustion or explosion. May decompose explosively on shock, friction or concussion. On combustion, forms toxic and corrosive gases.
10.2 Chemical stability
It is unstable under ordinary conditions, but it is stabilized by small additions of 2-nitrodiphenylamine and di-n-butyl sebacate.
10.3 Possibility of hazardous reactions
PROPYLENE GLYCOL DINITRATE is explosive. Acts as a strong oxidizing agent. Heating may cause a violent combustion or explosion producing toxic fumes (nitrogen oxides). May also decompose explosively from shock, friction or from a build-up of electrostatic charge that sparks suddenly to ground. Can begin a vigorous reaction that culminates in an explosion if mixed with reducing agents including hydrides, sulfides, and nitrides and numerous ordinary combustible materials. Reacts violently with Al, BP, cyanides, esters, PN2H, P, NaCN, SnCl2, sodium hypophosphite, and thiocyanates. Reacts with acids and with alkalis, including ammonia and amines. Must be stored in a cool, ventilated place, away from acute fire hazards and easily oxidized materials.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Ammonia compounds, amines, oxidizers, reducing agents, combustible materials ... Similar to ethylene glycol dinitrate in explosion potential.
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic fumes of nitrogen oxide
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 250 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is mildly irritating to the eyes. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Medical observation is indicated. See Notes.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
Using Otto fuel II (76% 1,2-propanediol dinitrate, 22.5% dibutyl sebacate, and 1.5% 2-nitrodiphenylamine) as substrate, 1,2-propanediol dinitrate was shown to be poorly biodegraded using an activated sewage sludge, a pure culture of Pseudomonas aeruginosa, and a commercially available inoculum employed for the degradation of nitrogen containing wastes(1).
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated for 1,2-propanediol dinitrate(SRC), using an estimated log Kow of 1.6(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc for 1,2-propanediol dinitrate can be estimated to be 68(SRC). According to a classification scheme(2), this estimated Koc value suggests that 1,2-Propanediol dinitrate is expected to have high mobility in soil(SRC).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: no data available | IMDG: no data available | IATA: no data available |
14.2 UN Proper Shipping Name
| ADR/RID: no data available | IMDG: no data available | IATA: no data available |
14.3 Transport hazard class(es)
| ADR/RID: no data available | IMDG: no data available | IATA: no data available |
14.4 Packing group, if applicable
| ADR/RID: no data available | IMDG: no data available | IATA: no data available |
14.5 Environmental hazards
| ADR/RID: No | IMDG: No | IATA: No |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| Propane-1,2-diyl dinitrate | Propane-1,2-diyl dinitrate | 6423-43-4 | 229-180-0 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Not Listed. | ||
| Vietnam National Chemical Inventory | Not Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Not Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Do NOT take working clothes home.
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
Propylene glycol dinitrate is included in Inorganic Acid Esters category.
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