1,2,3-Trichlorobenzene Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | 1,2,3-trichlorobenzene |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | 1,2,3-TRICHLORBENZOL; 1,2,6-trichlorobenzene; 1,2,3-TRICHLORBENZENE |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Industrial and scientific research uses. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed H317 May cause an allergic skin reaction H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment. |
| Response | P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P391 Collect spillage. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 1,2,3-trichlorobenzene | 1,2,3-trichlorobenzene | 87-61-6 | 201-757-1 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Inhalation may cause irritation of respiratory tract. Irritating to the eyes. May redden skin on contact. Ingestion may cause liver damage. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: May emit toxic hydrogen chloride and phosgene gases in fire. Behavior in Fire: Decomposes to form hydrogen chloride and phosgene gases in fire. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Use water spray, dry powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from strong oxidants. Keep in a well-ventilated room.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
MAK: 38 mg/m3, 5 ppm; peak limitation category: II(2); skin absorption (H); pregnancy risk group: C
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles.
Skin protection
Protective gloves.
Respiratory protection
Use local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | Solid. Flakes. |
|---|---|
| Colour | Colourless. |
| Odour | no data available |
| Melting point/freezing point | 53.5 °C. Atm. press.:Atmospheric pressure was not reported. |
| Boiling point or initial boiling point and boiling range | 218 °C. |
| Flammability | Combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 113 °C. |
| Auto-ignition temperature | > 500 °C. |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | dynamic viscosity (in mPa s) = 1.68. Temperature:50.0°C.;dynamic viscosity (in mPa s) = 0.91. Temperature:100.0°C. |
| Solubility | Insoluble (NTP, 1992) |
| Partition coefficient n-octanol/water | log Pow = 4.139. Temperature:25 °C. |
| Vapour pressure | 27.93 Pa. Temperature:25 °C. Remarks:0.21 mm Hg = 27.93 Pa. |
| Density and/or relative density | 1.45 g/cm³. Temperature:25 °C. |
| Relative vapour density | 6.25 (vs air) |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride. Reacts with strong oxidants.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
Slight when exposed to heat, flame, or oxidizers1,2,3-TRICHLOROBENZENE can react with oxidizing agents. (NTP, 1992). May emit toxic hydrogen chloride and phosgene gases in fire.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
On contact with acids or acid fumes they evolve highly toxic /hydrogen chloride/ fumes. chlorides
10.6 Hazardous decomposition products
When heated to decomp, it emits toxic fumes of /hydrogen chloride/. 2,3,6-trichlorobenzoic acid
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - > 5 000 mg/kg bw. Remarks:95% CL: Not applicable.
- Inhalation: no data available
- Dermal: LD50 DDY Mouse male percutaneous 300 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC100 - Danio rerio (previous name: Brachydanio rerio) - 30 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.46 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 0.9 mg/L - 96 h.
- Toxicity to microorganisms: IC50 - Nitrosomonas sp. - 96 mg/L - 24 h.
12.2 Persistence and degradability
AEROBIC: Sediment from freshwater streams in the Netherlands degraded trichlorobenzenes, with reported biodegradation half-lives of 50 to 323 days(1). Trichlorobenzene was biodegraded by an acclimated anaerobic sediment slurry obtained from the Tsurumi River, Japan(2). First-order biodegradation rate constants in the range of 0.030-0.017/days were reported for trichlorobenzene, corresponding to half-lives of about 23-41 days(2). The half-life of trichlorobenzene in sewage sludge amended soil was in the range of 23-35 days(3). Utilizing the Japanese MITI test(4), 0% of the theoretical BOD was reached over a 2 week incubation period in sludge, indicating that biodegradation of trichlorobenzene may not be an important environmental fate process(SRC).
12.3 Bioaccumulative potential
Sediments and animals collected from near the discharge zone of the Los Angeles County wastewater treatment plant were analyzed for 27 selected organic compounds /including trichlorobenzene/ that had been identified in the effluent. The sediment and tissue concn of these organic compounds were positively correlated with each other and with the n-octanol/water partition coefficient, but these were negatively correlated with the effluent concn.
12.4 Mobility in soil
Log Koc values of 3.6-3.9 were measured for trichlorobenzene in sediment obtained from Ise Bay, Japan(1) and log Koc values of 4.5-5.0 were measured from sediment of Lake Ketelmeer, Netherlands(2). According to a recommended classification scheme(3), these Koc values suggest that trichlorobenzene has low mobility in soil(SRC).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN2811 (For reference only, please check.) | IMDG: UN2811 (For reference only, please check.) | IATA: UN2811 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.) | IMDG: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.) | IATA: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 (For reference only, please check.) | IMDG: 6.1 (For reference only, please check.) | IATA: 6.1 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: I (For reference only, please check.) | IMDG: I (For reference only, please check.) | IATA: I (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: Yes | IMDG: Yes | IATA: Yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 1,2,3-trichlorobenzene | 1,2,3-trichlorobenzene | 87-61-6 | 201-757-1 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
UN number 2321 refers to liquid trichlorobenzenes.Liquid trichlorobenzenes are marine pollutants.See ICSCs 1049 and 344.
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
1,2,3-Trichlorobenzene is included in Hydrocarbons and Derivatives category.
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