2,4-Dichloronitrobenzene Safety Data Sheets

Characteristics

Products for Sale

SAFETY DATA SHEETS

According to the UN GHS revision 8

Version: 1.0

Creation Date: July 15, 2019

Revision Date: July 15, 2019

SECTION 1: Identification

1.1 GHS Product identifier

Product name	1,3-dichloro-4-nitrobenzene

1.2 Other means of identification

Product number	-
Other names	Nitro-2,4-dichlorobenzene; 2,4-DCNB; 1-Nitro-2,4-dichlorobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses	Industrial and scientific research uses.
Uses advised against	no data available

1.4 Supplier's details

Company	Echemi.com
Address	Echemi.com
Telephone	Echemi.com

1.5 Emergency phone number

Emergency phone number	Echemi.com
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

SECTION 2: Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Acute toxicity - Category 3, Dermal

Skin sensitization, Sub-category 1B

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 1B

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

2.2 GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H311 Toxic in contact with skin H317 May cause an allergic skin reaction H341 Suspected of causing genetic defects H350 May cause cancer H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P203 Obtain, read and follow all safety instructions before use. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

2.3 Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
1,3-dichloro-4-nitrobenzene	1,3-dichloro-4-nitrobenzene	611-06-3	210-248-3	100%

SECTION 4: First-aid measures

4.1 Description of necessary first-aid measures

If inhaled

Fresh air, rest.

Following skin contact

Rinse and then wash skin with water and soap.

Following eye contact

Rinse with plenty of water (remove contact lenses if easily possible).

Following ingestion

Rinse mouth.

4.2 Most important symptoms/effects, acute and delayed

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Aromatic hydrocarbons and related compounds

SECTION 5: Fire-fighting measures

5.1 Suitable extinguishing media

Fires involving this chemical can be controlled using a dry chemical, carbon dioxide, or Halon extinguisher. (NTP, 1992)

5.2 Specific hazards arising from the chemical

This chemical is combustible. (NTP, 1992)

5.3 Special protective actions for fire-fighters

Use powder, water spray, foam, carbon dioxide.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Do NOT let this chemical enter the environment.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Do NOT let this chemical enter the environment.

6.3 Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Separated from bases, strong oxidants and food and feedstuffs. Provision to contain effluent from fire extinguishing.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety spectacles.

Skin protection

Protective gloves.

Respiratory protection

Use ventilation (not if powder).

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

Physical state	Solid. Crystalline.
Colour	Yellow.
Odour	no data available
Melting point/freezing point	34 Â°C.
Boiling point or initial boiling point and boiling range	258.5 Â°C. Atm. press.:1 013 hPa.
Flammability	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit/flammability limit	no data available
Flash point	112 Â°C. Atm. press.:1 013 hPa.
Auto-ignition temperature	500 Â°C. Atm. press.:1 013 hPa.
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	no data available
Solubility	less than 0.1 mg/mL at 61Â° F (NTP, 1992)
Partition coefficient n-octanol/water	log Pow = 3.05.
Vapour pressure	0.01 hPa. Temperature:20 Â°C.
Density and/or relative density	1.48 g/cmÂ³. Temperature:80 Â°C.
Relative vapour density	(air = 1): 6.6
Particle characteristics	no data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes of nitrogen oxides and hydrogen chloride (see ICSC 0163). Reacts with strong oxidants and strong bases.

10.2 Chemical stability

no data available

10.3 Possibility of hazardous reactions

Can react vigorously with oxidizing materials. (NTP, 1992)

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

SECTION 11: Toxicological information

Acute toxicity

Oral: LD50 - rat - 379 mg/kg bw.
Inhalation: no data available
Dermal: LD50 - rat - 921 mg/kg bw.

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20Â°C.

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish: LC50 - Poecilia reticulata - 6.6 mg/L - 14 d.
Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 4.2 mg/L - 48 h.
Toxicity to algae: EC10 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 1.9 mg/L - 48 h.
Toxicity to microorganisms: EC50 - Tetrahymena pyriformis - 19.6 mg/L - 40 h.

12.2 Persistence and degradability

AEROBIC: Less than 0.1% of applied 2,4-dichloronitrobenzene was degraded in a 5 day biodegradation study using activated sludge from a municipal sewage treatment plant(1). However, since bacteria capable of degrading unspecified chloronitrobenzene isomers have been isolated, these compounds are not expected to be inherently recalcitrant(2).

12.3 Bioaccumulative potential

A BCF value of 84 was measured in guppies (Poecilia reticulata) during 3-day exposure to 2,4-dichloronitrobenzene(1). A 3-day exposure BCF of 80 was determined for golden ide fish (Leuciscus idus melanotus)(2). Rainbow trout, under continuous flow conditions and a water concentration of 750 ng/L, had a BCF value of 120 after 36 days exposure(3). According to a classification scheme(4), BCF values of 30 to 100 are moderate and 100 to 1000 are high. A 1-day exposure BCF of 150 was reported for green algae (Chlorella fusca)(2).

12.4 Mobility in soil

The Koc of 2,4-dichloronitrobenzene is estimated as 1,100(SRC), using a log Kow of 3.07(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2,4-dichloronitrobenzene is expected to have low mobility in soil.

12.5 Other adverse effects

no data available

SECTION 13: Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

14.1 UN Number

ADR/RID: UN2811 (For reference only, please check.)

IMDG: UN2811 (For reference only, please check.)

IATA: UN2811 (For reference only, please check.)

14.2 UN Proper Shipping Name

ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)

IMDG: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)

IATA: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)

14.3 Transport hazard class(es)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

14.4 Packing group, if applicable

ADR/RID: I (For reference only, please check.)

IMDG: I (For reference only, please check.)

IATA: I (For reference only, please check.)

14.5 Environmental hazards

ADR/RID: Yes

IMDG: Yes

IATA: Yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
1,3-dichloro-4-nitrobenzene	1,3-dichloro-4-nitrobenzene	611-06-3	210-248-3
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.
Korea Existing Chemicals List (KECL)			Listed.

SECTION 16: Other information

Information on revision

Creation Date	July 15, 2019
Revision Date	July 15, 2019

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Health effects of exposure to the substance have not been investigated adequately.

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

2,4-Dichloronitrobenzene is included in Organic Reagents category.