Diheptyl phthalate Safety Data Sheets

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity – single exposure, Category 3

Reproductive toxicity, Category 2

If inhaled

Following skin contact

Following eye contact

Following ingestion

Inhalation of vapors from very hot material may cause headache, drowsiness, and convulsions. Contact with eyes may cause irritation. (USCG, 1999)

Combustible.

Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Removal of phthalate esters (PAEs) by alpha-cyclodextrin (CD)-linked chitosan bead in aqueous solution was studied. Results of kinetic experiments indicated that diheptyl phthalate (DHpP) was adsorbed most efficiently (3.21 mg/g) ... It was concluded that the application of low cost alpha-CD-linked chitosan bead could have the potential to effectively remove PAEs from different aquatic environments.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on burning. This produces irritating fumes.

no data available

DIHEPTYL PHTHALATE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Can generate electrostatic charges. [Handling Chemicals Safely 1980. p. 250].

no data available

no data available

When heated to decomposition it emits acrid smoke and irritating fumes.

Acute toxicity

• Oral: no data available
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: no data available
• Toxicity to daphnia and other aquatic invertebrates: no data available
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

AEROBIC: Diheptyl phthalate present at 100 mg/L, reached 36% of its theoretical BOD in two weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1,4). Diheptyl phthalate, added to an aerobic semi-continuous activated sludge apparatus at 5, 10, and 20 mg/24 hr, underwent 52, 48, and 54% degradation, respectively(2-3). Di(heptyl,nonyl,undecyl) phthalate had a half-life of 6 to 8 days in river die-away tests(5). In active microcosms containing lake water and sediment, 40 to 48% of (14)C-di(heptyl,nonyl,undecyl) phthalate radioactivity was evolved as carbon dioxide over a 41 day period; after six weeks no residual (14)C-di(heptyl,nonyl,undecyl) phthalate was found in the water column and only 2 to 6% was associated with sediments(5). In semi-continuous activated sludge tests, a primary degradation half-life of <1 day at an addition rate of 5 to 200 mg/L per 24-hour cycle was observed for di(heptyl,nonyl,undecyl) phthalate(5). In shake flask studies using an acclimated bacterial inoculum, an ultimate degradation half-life of 5 days was observed for di(heptyl,nonyl,undecyl) phthalate at an initial concentration of 20 mg/L(5). Diheptyl phthalate was biodegraded in river water from the Kako River in Japan(6). Diheptyl phthalate was biodegraded 11-16% over a 40 day incubation period with activated sludge(7).

BCFs of 0.9 to 2.2 and 6.2 to 16.7 were measured for diheptyl phthalate in carp at chemical concentrations of 1 and 0.1 mg/L, respectively(1). According to a classification scheme(2), these measured BCFs suggest that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of diheptyl phthalate can be estimated to be 5.7X10+4(SRC). According to a classification scheme(2), this estimated Koc value suggests that diheptyl phthalate is expected to be immobile in soil. In sterile microcosms containing lake water and sediment, approximately 80% of di(heptyl,nonyl,undecyl) phthalate partitioned to sediment(3).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.