Aminol Safety Data Sheets

Acute toxicity - Category 4, Oral

Skin sensitization, Category 1

Serious eye damage, Category 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

If inhaled

Following skin contact

Following eye contact

Following ingestion

SYMPTOMS: Produces local irritation of skin, eyes and mucus membranes. ACUTE/CHRONIC HAZARDS: This chemical is toxic and a local irritant. (NTP, 1992)

This compound is combustible. (NTP, 1992)

Wear self-contained breathing apparatus for firefighting if necessary.

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

no data available

Most amine formulations have no shelf life limitations and are insensitive to light and temperature. 2,4-D

SALTS ARE NONFLAMMABLE ... /2,4-D SALTS/DMA 4 (DOW) 49 PERCENT 2,4- D, DIMETHYLAMINE SALT neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

no data available

no data available

When heated to decomposition it emits very toxic fumes of /hydrogen chloride, ammonia, & nitrogen oxides/.

Acute toxicity

• Oral: LD50 Rat oral 625 mg/kg
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50 Lepomis macrochirus (Bluegill) 166-542 mg/l/24 hr; 166-458 mg/l/48 hr /Conditions of bioassay not specified
• Toxicity to daphnia and other aquatic invertebrates: no data available
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

2,4-D dimethylamine is rapidly degraded by aquatic microorganisms in activated sewage at about the same rate as the free acid(1). The same study showed that biodegradation is sensitive to temperature, increasing by an order of magnitude for 2,4-D as the temperature is increased from 10 to 25 deg C(1). A half-life of 3.9 days was obtained for an unspecified amine salt of 2,4-D in a river-dieaway study(5). Half-lives obtained from other studies are: 10-11 days in plastic pools containing fish and hydrosoil, 6.6 days in Ft. Cobb Reservoir, 4.2 days in outdoor, artificial pool, 2.2 and 3.2 days in Louisiana ponds, 0.5-0.8 days in Okananagan Lake, British Columbia, 2.5-6.2 days for Melton Hill Reservoir in the Tennessee Valley Authority system, <1 day in Lake Seminole, and 2.5-6.2 days for Banks Lake, WA(5). While processes other than biodegradation may be contributing to the degradation in these studies, biodegradation is probably the key process(5). When the amine salts were sprayed onto field plots in Nova Scotia at 5.6, 11.2, and 22.4 kg/ha acid equivalent and soil cores sampled after 13 hr and 14, 28, 56, 70, 265, and 385 days, rapid decomposition of the 2,4-D was observed in the 14-42 day period following application and <5% remained at the end of 70 days(2). Highest 2,4-D concentrations were observed 14 days posttreatment(2). It is believed that the formulation was absorbed by the grass and later washed into the soil by rain and dew(2). A more recent field study looked into the persistence of 2,4-D applied as the dimethylamine salt in field plots in southern and northern Ontario as well as two forested areas in northern Ontario(3). In the two agricultural plots, 50% loss in the upper 10 cm of the soil profile occurred in 4 and 6 days(3). In the two forest plots characterized by sandy clay loam and fine sand soils, the half-lives were 7 and 23 days(2). The soil in the second case was characterized by lower pH and higher organic matter content, both of which might be expected to promote greater adsorption and longer persistence(3). Furthermore, the more rapid loss in clayey soil is consistent with the hypothesis that the 2,4-D is dissociated into its anions in most soils where it is more readily available to microorganisms(3). In a silt loam soil, over 70% of the ring carbon mineralized to CO2, about 20-25% was incorporated into soil as newly generated microbial tissue and about 1-2% remained undegraded after 58 days of incubation(6).

Bluegill (lepomis machrochirus) exposed outdoors in plastic pool to one 2 mg/l application of (14)c-labeled 2,4-d dimethylamine salt. during 12-wk exposure, incorporation of (14)c into fatty acids, glycogen & protein material accounted for 85% of (14)c activity.

The Koc for the 2,4-D dimethylamine ranged from 72 to 136 for 3 soils in 48 hr batch experiments using radiolabeled herbicide(1). According to a classification scheme(2), this estimated Koc value suggests that 2,4-D dimethylamine is expected to have high mobility in soil(SRC). Effluent breakthrough curves measured in the same soils showed that the 2,4-D dimethylamine was almost as mobile as the water at 5000 ppm but considerably slower at 50 ppm, a result consistent with the non-linear adsorption isotherms(1). Adsorption constants for 2,4-D dimethylamine ranged from 0.13 to 0.25(3,4); these values were calculated from a field study performed using a plastic pool containing clay-loam hydrosoil(3,4).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/