Picloram Safety Data Sheets

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

If inhaled

Following skin contact

Following eye contact

Following ingestion

Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin, respiratory system; nausea Target Organs: Eyes, skin, respiratory system, liver, kidneys (NIOSH, 2016)

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Use water spray, foam, powder, carbon dioxide.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Dry. Keep in a well-ventilated room. Separated from : see Chemical Dangers. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Keep containers closed. Do not cut or weld container.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on heating. This produces nitrogen oxides (see ICSC 0067, ICSC 0930) and hydrogen chloride (see ICSC 0163). Reacts with strong acids, strong bases and strong oxidants. This generates fire and explosion hazard.

Storage stability: a minimum of 2 years

Tordon 10k pellets are nonflammable.PICLORAM may be sensitive to prolonged exposure to light. Aqueous solutions may be decomposed by light. This chemical is incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. (NTP, 1992)

no data available

Hot concentrated alkali (hydrolyzes).

When heated to decomposition it emits very toxic fumes of /hydrogen chloride and nitrogen oxides/.

Acute toxicity

• Oral: LD50 Rat (male, Sprague-Dawley derived) oral 950 mg/kg (95% CI: 812-1120 mg/kg)
• Inhalation: no data available
• Dermal: LD50 Rabbit percutaneous >2000 mg/kg

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50; Species: Salvelinus namaycush (Lake trout) weight 0.3 g; Conditions: static without aeration, 10 deg C, pH 7.2-7.5, alkalinity 30-35 mg/L, hardness 40-50 mgL as CaCO3; Concentration: 4.3 mg/L for 96 hr @ 10 deg C (95% confidence limit 4.0-4.5 mg/L), /Technical material 90-100%
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) 1st instar larva; Conditions: freshwater, static; Concentration: 68300 ug/L for 48 hr (95% confidence interval: 63000-75000 ug/L); Effect: intoxication, immobilization /93.8% purity
• Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: 36790 ug/L for 96 hr (95% confidence interval: 35100-38750 ug/L); Effect: population abundance /93.4% purity
• Toxicity to microorganisms: no data available

AEROBIC: Possible pathways for aerobic primary degradation of picloram are decarboxylation or amino displacement(1). Soil half-lives for picloram at various initial concentrations were 55 days at 0.25 ppm (7 days lag-phase), 90 days at 0.5 ppm (30 days lag phase), and 180 days at 1.0 ppm (90 days lag phase)(2). Picloram was degraded through aerobic metabolism in seven soils, half-lives ranging from 167 to 513 days, with carbon dioxide being the major degradate(3). Aerobic degradation half-lives for picloram at various application rates were 18 days at 0.0025 ppm, 29 days at 0.025 ppm, 150 days at 0.25 ppm, and 300 days at 2.5 ppm(4). After 100 days incubation in 3 soil types, remaining picloram concentrations were 63 to 77% of the initial concentrations(5). Degradation of 75 to 100% picloram in soils required 18 months(6). No detectable degradation of picloram was observed in 8 weeks in soil with high organic matter content from Pentego, NC(7). In the presence of a mixture containing 0.5% fertile garden soil, yeast, and other organics, picloram persisted >275 days(8). In a 423 day period using a picloram concentration of 0.4 ppm, some soils had 52 to 82.5% of the picloram decomposed and others had only 5.2 and 7.6% decomposed(9). Degradation of picloram in thirteen soils after incubation for 6 months ranged from 0 to 60% at 3 mg/L, from 0 to 84% at 1.5 mg/L, from 5 to 94% at 0.75 mg/L, from 28 to 99% at 0.375 mg/L, from 38 to >99% at 0.188 mg/L, from 32 to >99% at 0.094 mg/L, from 28 to >99% at 0.047 mg/L(10). Most of the soils showed a tendency towards greater percentage detoxification for lower concentrations(10). Picloram was applied at a rate of 10 ppm to five different soils, after 124 days of alternating wet and drying cycles, picloram remained in the soil 82.7 to 91.0% incubated at 30 deg C and 86.0 to 93.0% incubated at 50 deg C(11). The amount of non-degraded picloram in groundwater from 4 sites after incubation for 15 weeks (105 days) was 60.8 to 82.4% (average 71.6%) at an initial concentration of 0.72 ppm, and 60.7 to 79.8% (average 67.9%) at an initial concentration of 10.0 ppm(12).

BCFs of 0.11 and 0.54 were reported in bluegill sunfish exposed for 28 days at C14 labeled picloram concentrations of 1.0 and 0.1 mg/L, respectively, using a flow-thru system(1). The BCF of picloram in fish was also measured as 31 using the flowing water method(2-3). According to a classification scheme(4), these BCF values suggest bioconcentration in aquatic organisms is low(SRC).

Experimental Koc values for picloram are 12.7(1-2), 25.2(3), 0.026(4), 17(5), and 25.5(6). Koc values for picloram in soils were 11.1, 22.1, 11.2, 12.5, 18.0, 20.6 and 9.9 at 0.74, 2.92, 1.03, 1.36, 0.45, 1.89, and 1.17% organic carbon, respectively(7). Koc values for 28 different types of pasture soils with varying amounts of organic carbon ranged from 14 to 100(8). According to a classification scheme(9), these Koc values suggest that picloram is expected to have very high to high mobility in soil. The pKa of picloram is 2.3(10), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to organic carbon and clay than their neutral counterparts(11). Leaching potential is greatest in sandy soils low in organic matter(12-13). Picloram is usually confined to the upper 1 foot (30 cm) when application rates are low (<1 lb/acre, <1.12 kg/ha), but that picloram can readily move to depths >3 feet (approximately 1 meter), even in relatively dry areas, when the application rate is high (3 to 9 lb/acre, 3 to 10 kg/ha)(16).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.