Wood creosote Safety Data Sheets

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Skin corrosion, Sub-category 1B

Skin sensitization, Category 1

Acute toxicity - Category 4, Inhalation

Germ cell mutagenicity, Category 2

Specific target organ toxicity – repeated exposure, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

If inhaled

Following skin contact

Following eye contact

Following ingestion

SYMPTOMS: Symptoms of exposure to this compound include pigmentation, skin irritation and inflammation; dermatitis, nausea, vomiting, abdominal pain, headache, vertigo, dizziness, faintness, cyanosis, collapse, difficulty breathing, convulsions, erythema, vesiculation, blistering, ulceration, gangrene, kidney and liver damage; chronic lung disease, hypothermia and coma. Other symptoms include sensation of burning and itching; conjunctivitis with mild hyperemia, photophobia and discharge; and keratoconjunctivitis, involving loss of corneal epithelium, clouding of the cornea, long-lasting irritability, miosis and photophobia. This compound may also cause salivation, respiratory difficulties, thready pulse, loss of pupillary reflexes, keratitis and corneal abrasion. ACUTE/CHRONIC HAZARDS: This compound is irritating to the skin and eyes. (NTP, 1992)

SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes, muscular weakness, cardiovascular collapse and paralysis of the vasomotor centers. Ingestion produces burning in the mouth and throat, gastrointestinal distress, tremors and collapse. ACUTE/CHRONIC HAZARDS: This compound is an irritant and is easily absorbed through the skin. When heated to decomposition it emits toxic fumes. (NTP, 1992)

This chemical is combustible. (NTP, 1992)

This chemical is combustible. (NTP, 1992)

Wear self-contained breathing apparatus for firefighting if necessary.

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

Personal protection: complete protective clothing, face shield and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in covered containers as far as possible.

Wear approved respiratory protection, chemically compatible gloves and protective clothing. Wipe up spillage or collect spillage using a high efficiency vacuum cleaner. Avoid breathing vapor or dust. Ventilate area and wash spill site. Place spillage in appropriately labelled container for disposal.

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs.Store in tight, light-resistant container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

On combustion, forms toxic fumes.

Darkens on exposure to air and light

This material is combustible when exposed to heat or flame.Phenols, such as CREOSOTE, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has pKa = 9.88). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. This compound is incompatible with acacia, albumin, oxidizers and cupric, ferric, gold and silver salts. (NTP, 1992)

no data available

no data available

When heated to decomposition material emits acrid smoke and irritating fumes.

Acute toxicity

• Oral: LD50 Rat oral 725 mg/kg
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: no data available
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age 12 hr); Conditions: freshwater, static, 18 deg C; Concentration: 25900 ug/L for 48 hr; Effect: intoxication, immobilization /formulation
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

AEROBIC: o-Methoxyphenol, present at 100 mg/L, reached 97% of its theoretical BOD in four weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1).

An estimated BCF of 3 was calculated in fish for o-methoxyphenol(SRC), using log Kow of 1.32(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

A log Koc of 1.60 for o-methoxyphenol, corresponding to a Koc of 40(SRC), was experimentally determined in a Brookston clay loam soil(1). A log Koc of 1.56(2), corresponding to a Koc of 36(SRC) has also been reported. According to a classification scheme(3), these Koc values suggest that o-methoxyphenol is expected to have very high mobility in soil. The pKa of o-methoxyphenol is 9.98(4), indicating that this compound will exist primarily in the undissociated form in the environment(SRC). The adsorption of the phenol occurrs by hydrogen bonding to sites on soil surfaces; ortho-substitution generally results in decreased adsorption compared to para-substitution due to steric hindrance(1).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/