Side Effects Of Astrazeneca You Didn't Know About

What is AstraZeneca?

AstraZeneca, the full name of Oxford-AstraZeneca vaccine, is a viral vector vaccine of ChadoX 1-S [recombinant]. This vaccine is a vaccine that removes the highly virulent adenovirus. Since the vectors and spikes associated with the novel coronavirus are loaded into the virus, it exerts immunity by stimulating the body to produce corresponding antibodies in the human body. Studies have shown that chadOX1-S has a potency of 63.09% and is more suitable for use in low- and middle-income countries due to its ease of storage. Since the advent of the AstraZeneca vaccine, it has been accompanied by many controversies and side effects. However, in the context of global emergency prevention and control, many countries still choose to arrange vaccination. For example, the AstraZeneca vaccine has been widely used in Europe, but its side effects have become increasingly apparent during the vaccination process. Such as causing side effects such as thrombosis, serious harm to human health, and even lead to death.

Several side effects of AstraZeneca

1. Capillary Leak Syndrome (CLS)

Capillary leak syndrome, a rare and dangerous blood disorder, has been added to the list of potential side effects of AstraZeneca's vaccine. After inoculation, capillary endothelial cells are damaged, vascular permeability increases, causing capillary edema, and a large amount of plasma protein infiltrates into the interstitial space, resulting in clinical manifestations such as hypoalbuminemia, hypovolemic shock, and acute renal ischemia. Capillary leak syndrome should be listed as a side effect of the AstraZeneca vaccine in the product description to alert health care providers and patients of the risks.

2. Thrombosis

Blood clots are second side effect of AstraZeneca and carry a high risk of death. Figures show that 1 in 50,000 people under the age of 50 treated with AstraZeneca develops a blood clot. It usually occurs in young, healthy vaccinated people. The scientists noted that in associated cases of venous thrombosis, decreased platelet levels and specific antibodies that activate platelets were found. The state of immune antibodies can cause platelets to incorrectly clump together to form a clot, which further activates the clotting mechanism elsewhere in the body, leading to multiple venous thrombosis. Once thrombus is formed, most of them will be accompanied by severe symptoms, such as hemiplegia and aphasia of cerebral infarction; severe precordial colic in myocardial infarction; severe chest pain, dyspnea, hemoptysis caused by pulmonary infarction; thrombosis in lower limbs will cause Pain in both legs, or coldness and intermittent claudication. It should be actively controlled to prevent adverse consequences.

3. Flu-like symptoms

Flu-like symptoms are third side effect of AstraZeneca , along with high temperatures, sore throat, runny nose, cough and chills. If you do not seek medical attention in time, it will cause serious bacterial infection, affect the heart and heart muscle, cause inconvenience of movement, long-term lack of energy, and damage the liver and kidney function and respiratory system. In this case, patients should pay attention to rest, avoid colds, drink plenty of water, and maintain indoor ventilation and hygiene.

Measures to deal with side effects of AstraZeneca

Relevant health departments should conduct in-depth investigations, focus on the vaccinated population, comprehensively consider from the perspective of weighing the pros and cons, focus on identifying the potential risks that may be brought about by vaccination at different ages, further study the immune mechanism, and find out the stimulation of the body to produce such adverse reactions. the elements of. Mechanisms and components, and specific vaccinations when necessary, to achieve safe and effective vaccination outcomes.

Precautions for getting the AstraZeneca vaccine

Before vaccination, you should learn about vaccine-related knowledge and vaccination procedures in advance; understand your physical condition, take a good rest, and keep your body in a better physiological state. It is best not to vaccinate on an empty stomach. If you experience an adverse reaction after a vaccine, seek medical attention immediately.

Conclusion

Vaccine-related adverse reactions are not uncommon in the history of human vaccine development, but in the vast majority of cases, the protective effect of vaccination far outweighs the potential risk of adverse reactions. Everything has two sides. Although the safety of AstraZeneca has always been questioned, we should look at the problem with dialectical thinking and reasonably understand our own strengths and weaknesses.