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Familial hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disease. The pathogenesis of this disease is the absence or abnormality of LDL receptors on the cell membrane surface, which leads to abnormal LDL metabolism in the body, resulting in increased plasma total cholesterol (TC) levels and low-density lipoprotein-cholesterol (LDL-C) levels.
  • Site of disease:

    Blood vessels
  • Infectious :

    Not contagious
  • Frequent population:

    All groups
  • Related symptoms:

    Nodules atherosclerosis vascular bruits calcification high plasma cholesterol levels
  • Concurrent disease:

Related Drugs
Simvastatin Tablets
Indication: 1. Hyperlipidemia (1) For patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hypercholesterolemia, when dietary control and other non-drug treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides. Simvastatin also increases high-density lipoprotein cholesterol, thereby reducing the ratio of low-density lipoprotein/high-density lipoprotein and total cholesterol/high-density lipoprotein. (2) For patients with homozygous familial hypercholesterolemia, when dietary control and non-dietary treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B. 2. Coronary heart disease. (1) Reduce the risk of death. (2) Reduce the risk of death from coronary heart disease and non-fatal myocardial infarction. (3) Reduce the risk of stroke and transient ischemic attack. (4) Reduce the risk of myocardial revascularization surgery (coronary artery bypass grafting and percutaneous balloon coronary angioplasty). (5) Delay the progression of atherosclerosis, including the occurrence of new lesions and complete blockage.
Simvastatin Tablets
Indication: 1. Hyperlipidemia (1) For patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hypercholesterolemia, when dietary control and other non-drug treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides. Simvastatin also increases high-density lipoprotein cholesterol, thereby reducing the ratio of low-density lipoprotein/high-density lipoprotein and total cholesterol/high-density lipoprotein. (2) For patients with homozygous familial hypercholesterolemia, when dietary control and non-dietary treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B. 2. Coronary heart disease. (1) Reduce the risk of death. (2) Reduce the risk of death from coronary heart disease and non-fatal myocardial infarction. (3) Reduce the risk of stroke and transient ischemic attack. (4) Reduce the risk of myocardial revascularization surgery (coronary artery bypass grafting and percutaneous balloon coronary angioplasty). (5) Delay the progression of atherosclerosis, including the occurrence of new lesions and complete blockage.
Simvastatin Tablets
Indication: 1. Hyperlipidemia (1) For patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hypercholesterolemia, when dietary control and other non-drug treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides. Simvastatin also increases high-density lipoprotein cholesterol, thereby reducing the ratio of low-density lipoprotein/high-density lipoprotein and total cholesterol/high-density lipoprotein. (2) For patients with homozygous familial hypercholesterolemia, when dietary control and non-dietary treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B. 2. Coronary heart disease. (1) Reduce the risk of death. (2) Reduce the risk of death from coronary heart disease and non-fatal myocardial infarction. (3) Reduce the risk of stroke and transient ischemic attack. (4) Reduce the risk of myocardial revascularization surgery (coronary artery bypass grafting and percutaneous balloon coronary angioplasty). (5) Delay the progression of atherosclerosis, including the occurrence of new lesions and complete blockage.
Simvastatin Tablets
Indication: 1. Hyperlipidemia (1) For patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hypercholesterolemia, when dietary control and other non-drug treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprotein B and triglycerides. Simvastatin also increases high-density lipoprotein cholesterol, thereby reducing the ratio of low-density lipoprotein/high-density lipoprotein and total cholesterol/high-density lipoprotein. (2) For patients with homozygous familial hypercholesterolemia, when dietary control and non-dietary treatments are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B. 2. Coronary heart disease. (1) Reduce the risk of death. (2) Reduce the risk of death from coronary heart disease and non-fatal myocardial infarction. (3) Reduce the risk of stroke and transient ischemic attack. (4) Reduce the risk of myocardial revascularization surgery (coronary artery bypass grafting and percutaneous balloon coronary angioplasty). (5) Delay the progression of atherosclerosis, including the occurrence of new lesions and complete blockage.
Ezetimibe Tablets
Indication: Primary hypercholesterolemia: This product can be used alone or in combination with HMG-CoA reductase inhibitors (statins) as an adjunctive therapy in addition to dietary control to treat primary (heterozygous familial or non-familial) hypercholesterolemia, and can reduce total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B (ApoB). Homozygous familial hypercholesterolemia (HoFH): This product can be used in combination with statins as an adjunctive therapy to other lipid-lowering therapies (such as LDL-C plasmapheresis), or to reduce TC and LDL-C levels in HoFH patients when other lipid-lowering therapies are ineffective. Homozygous sitosterolemia (or phytosterolemia): This product is used as an adjunctive therapy in addition to dietary control to reduce the levels of sitosterol and phytosterols in patients with homozygous familial sitosterolemia.
Lovastatin Tablets
Indication: Used to treat hypercholesterolemia and combined hyperlipidemia.
Manufacturer:

Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.

Pravastatin Sodium Tablets
Indication: Hyperlipidemia, familial hypercholesterolemia.
Manufacturer:

Daiichi Sankyo Pharmaceutical (SHANGHAI) Co., Ltd.

Pravastatin Sodium Tablets
Indication: Hyperlipidemia, familial hypercholesterolemia.
Manufacturer:

Daiichi Sankyo Pharmaceutical (SHANGHAI) Co., Ltd.

Rosuvastatin Calcium Tablets
Indication: 1. This product is suitable for primary hypercholesterolemia (type IIa, including heterozygous familial hypercholesterolemia) or mixed dyslipidemia (type IIb) whose dyslipidemia cannot be properly controlled by diet control and other non-drug treatments (such as exercise therapy, weight loss). 2. This product is also suitable for patients with homozygous familial hypercholesterolemia as an adjuvant treatment for diet control and other lipid-lowering measures (such as LDL removal therapy), or when these methods are not applicable.
Rosuvastatin Calcium Tablets
Indication: 1. This product is suitable for primary hypercholesterolemia (type IIa, including heterozygous familial hypercholesterolemia) or mixed dyslipidemia (type IIb) whose dyslipidemia cannot be properly controlled by diet control and other non-drug treatments (such as exercise therapy, weight loss). 2. This product is also suitable for patients with homozygous familial hypercholesterolemia as an adjuvant treatment for diet control and other lipid-lowering measures (such as LDL removal therapy), or when these methods are not applicable.
Manufacturer:

Lunan BETTER Pharmaceutical Co., Ltd.

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