Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple systems and organs and has multiple autoantibodies. Tissue damage is caused by a large number of pathogenic autoantibodies and immune complexes in the body. Clinically, there may be manifestations of damage to various systems and organs, such as skin, joints, serous membranes, heart, kidneys, central nervous system, blood system, etc. The disease occurs worldwide, with a prevalence of 4/100,000 to 25/100,000. The prevalence is higher in Asia and blacks, and the prevalence in my country is 70/100,000 to 75/100,000. The incidence in women is significantly higher than that in men, about 10:1. The peak incidence is in women of childbearing age, and the elderly and children may also be ill. This disease belongs to the category of Yin-Yang poison, Yang poison spot, butterfly spot, sunburn sore, ghost face sore, and face wandering wind in traditional Chinese medicine.