Around the perimenopause period, due to the gradual decline of ovarian function to cessation of ovarian function, the gradual loss of estrogen production leads to a series of physiological changes in the external genitalia, mainly atrophic changes of varying degrees. Usually, the skin shows aging characteristics around the age of 40, and the changes are obvious 5 to 10 years after menopause. Vulvar white lesions refer to a group of diseases with tissue degeneration and pigment changes caused by nutritional disorders of the vulvar skin and mucous membranes. It is characterized by extreme itching, ulceration, severe pain, and skin changes in the vulva. It is difficult to treat and is prone to recurrence, causing great pain to patients. This disease is a chronic pathological process with varying lengths of course, up to several decades in the elderly. Because the cause is still unclear, the relevant naming and treatment methods are not unified. In the past, vulvar diseases in which the skin and mucous membranes of the vulva became white, thickened or atrophied were collectively referred to as vulvar leukoplakia, and it was even considered a precancerous lesion. Therefore, early excision was advocated at that time. Later, some people believed that vulvar leukoplakia could only be diagnosed if atypical proliferative cells were found in pathological sections. Due to different diagnostic criteria, disease nature and prognosis, there is confusion in the understanding and treatment of this disease. In order to unify the understanding, many scholars at home and abroad have conducted further retrospective investigation, analysis and discussion on the naming and classification of white lesions of the vulva. In 1877, Schwimmer first named the whitening and hyperkeratosis of the buccal mucosa as leukoplakia. Later, Breisky reported similar lesions in the vulva in 1985 and named it vulvar leukoplakia. Later, Taussig (1923, 1930) classified vulvar leukoplakia into early (hypertrophic) and late (atrophic) stages of vulvar leukoplakia. This view has been used by later generations. In 1961, Oberqield reviewed relevant literature and observed his own materials, suggesting that the atrophic stage of Taussig's vulvar leukoplakia was actually lichen sclerosus atrophicus. However, Clark and Woodruqq used the radionuclide method and confirmed through the determination of 3H (tritium) labeled thymidine that the thinned epidermis of lichen sclerosus atrophicus had vigorous metabolic function and did not atrophy. Therefore, some people believe that the name of lichen sclerosus atrophicus is not appropriate, and the word atrophy should be removed and it should be renamed lichen sclerosus. Some people even believe that the initial lesions and inherent lesions of this disease are damage to the subepidermal connective tissue fibers and matrix, and the thinning of the epidermis is secondary, which is consistent with the opinions of Oberqield and Stelguler, so in terms of the formation mechanism, it is believed that the name lichen sclerosus is more accurate. For a long time, clinically, the whitening of the vulva has been called vulvar leukoplakia. In the past 20 years, the concept of leukoplakia has been limited to atypical hyperplasia under the mucosal epidermis. The same term has different meanings. In order to avoid confusion, most scholars advocate the abandonment of the name of vulvar leukoplakia. The 9th International Conference on Vulvar Diseases in 1987 proposed a new classification and naming as follows: ① Non-neoplastic skin and mucosal epithelial lesions include lichen sclerosus, squamous epithelial hyperplasia, and other skin diseases; ② Vulvar intraepithelial neoplasia (VIN) includes mild, moderate, and severe atypical hyperplasia and carcinoma in situ. There is no unified naming in China so far, and scholars name and classify according to their own opinions. Some authors believe that the initial clinical diagnosis cannot determine whether there is atypical hyperplasia. Therefore, before pathological examination, they can generally be collectively referred to as vulvar white lesions or vulvar leukoderma, including proliferative vulvar skin lesions and lichen sclerosus, vulvar atypical hyperplasia, vulvar vitiligo, etc.