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Home > Drugs > Vildagliptin Registered Holders
51 Related Holders
Vildagliptin structure

Vildagliptin structure

Vildagliptin

Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.IC50 Value: 2.3 nM[1]Target: DPP-4in vitro: Vildagliptin is an N-substituted glycyl-2-cyanopyrrolidine (figure 2). It is a potent competitive and reversible inhibitor of human and rodent DPP-4 in vitro, with a median inhibitory concentration (IC50) ~2-3 nmol/L. Importantly, vildagliptin inhibits DPP-4 with high specificity relative to other similar peptidases where its IC50 exceeds 200 mol/L [1].in vivo: Compared to a

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INNOVARE LABS PRIVATE LTD
United States United States

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CHIERON A INGREDIENTS PRIVATE LTD
United States United States

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MANKIND PHARMA LTD
United States United States

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OPTIMUS DRUGS PRIVATE LTD
United States United States

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HONOUR LAB LTD
United States United States

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VIWIT PHARMACEUTICAL CO LTD
United States United States

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LEE PHARMA LTD
United States United States

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JUBILANT PHARMOVA LTD
United States United States

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HIKAL LTD
United States United States

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Exemed Pharmaceuticals
United States United States

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