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Vildagliptin structure

Vildagliptin

Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.IC50 Value: 2.3 nM[1]Target: DPP-4in vitro: Vildagliptin is an N-substituted glycyl-2-cyanopyrrolidine (figure 2). It is a potent competitive and reversible inhibitor of human and rodent DPP-4 in vitro, with a median inhibitory concentration (IC50) ~2-3 nmol/L. Importantly, vildagliptin inhibits DPP-4 with high specificity relative to other similar peptidases where its IC50 exceeds 200 mol/L [1].in vivo: Compared to a

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Guangzhou Greensyn Pharma Co., Ltd.

China

API Registration Country

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Founded in:

2000-12-08
Country:

China
Address:

Units 610-612, 614-616, 6th Floor, Zone D, Science and Technology Innovation Base, No. 80, Lanyue Road, Science City, Huangpu District, Guangzhou.
Tax NO.:

91440116707560239T
Registered Funds:

50 million yuan
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Zhejiang Tianyu Pharmaceutical Co., Ltd.

China

API Registration Country

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Founded in:

2003-02-14
Country:

China
Address:

Taizhou Huangyan Jiangkou Chemical Development Zone
Tax NO.:

91331000148144211K
Registered Funds:

347.977159 yuan
Website:

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Jiangxi Synergy Pharmaceutical Co., Ltd.

China

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Founded in:

2004-04-20
Country:

China
Address:

Jiangxi Fengxin High-tech Industrial Park, Fengxin County, Yichun City, Jiangxi Province
Tax NO.:

913609007599770366
Registered Funds:

421.52735 million yuan
Website:

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Hainan General Sanyang Pharmaceutical Co., Ltd.

China

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Founded in:

2001-08-20
Country:

China
Address:

No. 8 Haili Road, Xiuying District, Haikou City
Tax NO.:

91460000730051264Q
Registered Funds:

100 million yuan
Website:

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Hunan Jiudian HONGYANG Pharmaceutical Co., Ltd.

China

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Founded in:

2015-06-26
Country:

China
Address:

Tongguan Circular Economy Industrial Base, Wangcheng Economic Development Zone, Hunan
Tax NO.:

91430122344723202P
Registered Funds:

233.7295 million yuan
Email:

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Second PHARMA Co., Ltd.

China

API Registration Country

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Founded in:

2003-06-17
Country:

China
Address:

No. 33, Weiwu Road, Shangyu Economic and Technological Development Zone, Hangzhou Bay, Zhejiang Province
Tax NO.:

91330604751186571F
Registered Funds:

80.12 million yuan
Email:

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Zhe JIANG HUA HAI Pharmaceutical Co., Ltd.

China

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Founded in:

2001-02-28
Country:

China
Address:

Xunqiao, Linhai City, Zhejiang Province
Tax NO.:

91330000147968817N
Registered Funds:

1.491754938 yuan
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Zhejiang Guobang Pharmaceutical Co., Ltd.

China

API Registration Country

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Founded in:

2004-08-06
Country:

China
Address:

No. 6, Weiwu Road, Shangyu Economic and Technological Development Zone, Hangzhou Bay, Zhejiang Province
Tax NO.:

913306007258898636
Registered Funds:

138.8 million yuan
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Shandong Keyuan Pharmaceutical Co., Ltd.

China

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Founded in:

2004-12-27
Country:

China
Address:

Keyuan Street, Shandong Shanghe Economic Development Zone, Jinan City, Shandong
Tax NO.:

91370126771003840T
Registered Funds:

108.29 million yuan
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Shandong Luoxin Pharmaceutical Group HENGXIN Pharmaceutical Co., Ltd.

China

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Founded in:

2011-04-11
Country:

China
Address:

West side of Yanbin Road, Feixian Economic Development Zone
Tax NO.:

913713255728813685
Registered Funds:

50 million yuan
Email:

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