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Vildagliptin structure

Vildagliptin

Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.IC50 Value: 2.3 nM[1]Target: DPP-4in vitro: Vildagliptin is an N-substituted glycyl-2-cyanopyrrolidine (figure 2). It is a potent competitive and reversible inhibitor of human and rodent DPP-4 in vitro, with a median inhibitory concentration (IC50) ~2-3 nmol/L. Importantly, vildagliptin inhibits DPP-4 with high specificity relative to other similar peptidases where its IC50 exceeds 200 mol/L [1].in vivo: Compared to a

Find 51 Related Holders

Qilu Pharmaceutical Co., Ltd.

China

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Founded in:

1992-08-21
Country:

China
Address:

No. 317, Xinluo Street, High-tech Zone, Jinan City, Shandong Province
Tax NO.:

91370000614073351Q
Registered Funds:

600 million yuan
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Jinan MINGXIN Pharmaceutical Co., Ltd.

China

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Founded in:

2003-02-14
Country:

China
Address:

No. 3 Road, Longshan Industrial Park, Zhangqiu City, Jinan City
Tax NO.:

913701007465770173
Registered Funds:

50 million yuan
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Yangtze River Pharmaceutical Group Jiangsu HaiCi Biological Pharmaceutical Co., Ltd.

China

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Founded in:

2005-02-22
Country:

China
Address:

No. 8, Taizhen Road, Taizhou Pharmaceutical Hi-tech Zone, Jiangsu Province
Tax NO.:

91321200771524291U
Registered Funds:

200 million yuan
Website:

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Nanjing YOKO Pharmaceutical Co., Ltd.

China

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Founded in:

2003-02-08
Country:

China
Address:

No. 28, Hengjing Road, Nanjing Economic and Technological Development Zone
Tax NO.:

91320192745372941T
Registered Funds:

66 million yuan
Email:

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Shandong Langnuo Pharmaceutical Co., Ltd.

China

API Registration Country

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Founded in:

2012-05-21
Country:

China
Address:

No. 127, Qizhong Avenue, Yanbei Subdistrict Office, Qihe County, Dezhou City, Shandong Province
Tax NO.:

91371425596574565F
Registered Funds:

60 million yuan
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Nanjing Sanhome Pharmaceutical Co., Ltd.

China

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Founded in:

1996-09-19
Country:

China
Address:

No. 9 Huizhong Road, Nanjing Economic and Technological Development Zone
Tax NO.:

91320192608959455D
Registered Funds:

430 million yuan
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NORTHEAST Pharmaceutical Group Co., Ltd.

China

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Founded in:

1993-06-10
Country:

China
Address:

Kunming Lake Street, Shenyang Economic and Technological Development Zone
Tax NO.:

91210100243490227Y
Registered Funds:

1,429,103,265 yuan
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Jiangsu Disainuo Pharmaceutical Co., Ltd.

China

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Founded in:

2006-10-11
Country:

China
Address:

No. 3, Kang'an Road, Liyang Economic Development Zone, Jiangsu Province
Tax NO.:

91320481792322090C
Registered Funds:

100 million yuan
Website:

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JIANGXI SYNERGY PHARMACEUTICAL CO LTD

United States

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Tianjin Minxiang Pharmaceutical Co., Ltd.

Japan

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