Guangzhou Baiyunshan Pharmaceutical Co.,ltd.baiyunshan Hejigong Pharmaceutical Factory

It has the effect of directly stimulating vascular α1 receptors and causing vasoconstriction, thereby alleviating congestion and edema caused by inflammation

A highly effective fluorinated and chlorinated corticosteroid with anti-inflammatory, antipruritic and vasoconstrictive effects. It increases cAMP concentration in cells and inhibits the release of histamine by increasing the responsiveness of β receptors to catecholamine, activating adenylate cyclase to increase CAMP production, and inhibiting phosphoethylesterase to reduce CAMP destruction. Its effect in inhibiting granuloma proliferation in rats and mice is similar to that of dexamethasone.

This product is an imidazole antifungal drug with a broad spectrum of anti-dermatophytes, yeasts, filamentous fungi and dimorphic fungi, and has strong antibacterial activity. It is also effective against Malassezia furfur and Gram-positive cocci. This drug has a good effect on experimental dermatophytosis in animals. Like other imidazole drugs, this product has an inhibitory effect on C14-demethylation, preventing it from forming ergosterol, and can also reduce the production of mevalonic acid so that it cannot form squalene, thereby affecting the synthesis of fungal ergosterol.

This product belongs to the macrolide antibiotics, and has antibacterial activity against Staphylococcus, various groups of Streptococcus and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. may also be sensitive to this product. This product also has antibacterial activity against various anaerobic bacteria except Bacteroides fragilis and Fusobacterium; it also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis. This product is only effective against bacteria that actively divide.