SPH NO.1 Biochemical & Pharmaceutical Co., Ltd.

It can cause blood vessels to contract, reduce capillary permeability, enhance platelet aggregation and adhesion, promote platelets to release coagulation active substances, shorten coagulation time, and achieve hemostatic effect.

A cyanocobalamin analog of vitamin B12, it is an important coenzyme for the synthesis of nucleotides in cells, participates in methyl conversion and folic acid metabolism in the body, and promotes the reduction of methylfolate to tetrahydrofolate; it participates in the tricarboxylic acid cycle, is very important for the formation of lipoproteins in the nerve myelin, and can keep sulfhydryl enzymes in an active state, thereby participating in a wide range of protein and fat metabolism. It can promote the development and maturation of red blood cells, and is a necessary factor for the complete formation of nerve sheath spinal cord fibers and maintaining the function of epithelial cells in the digestive system.

This product is a congener of cyanocobalamin B12. It is an important coenzyme for the synthesis of nucleotides in cells, participates in methyl conversion and folic acid metabolism in the body, and promotes the reduction of methylfolate to tetrahydrofolate; it also participates in the tricarboxylic acid cycle, which is very important for the formation of lipoproteins in nerve myelin, and can keep sulfhydryl enzymes in an active state, thereby participating in a wide range of protein and fat metabolism. This product can promote the development and maturation of red blood cells, which is a necessary factor for the complete formation of nerve sheath spinal cord fibers and maintaining the function of epithelial cells in the digestive system.

It stimulates the contraction of uterine smooth muscles, simulates the contraction of uterus during normal delivery, and causes cervical dilation; it stimulates the contraction of mammary smooth muscles, which helps milk to be discharged from the breast, but does not increase the amount of milk secretion from the mammary gland.

This product belongs to the aminoglycoside antibiotics. The antibacterial spectrum is similar to that of gentamicin. It has antibacterial effects on Gram-negative bacteria such as Escherichia coli, aerogenes, Klebsiella, Proteus mirabilis, some indole-positive Proteus, Pseudomonas aeruginosa, some Neisseria, some non-pigmented Serratia and Shigella; the antibacterial effect of this product on Pseudomonas aeruginosa is 3 to 5 times stronger than that of gentamicin, and Pseudomonas aeruginosa that is moderately sensitive to gentamicin is highly sensitive to this product. Among Gram-positive bacteria, Staphylococcus aureus (including β-lactamase-producing strains) is sensitive to this product; Streptococci (including Streptococcus pyogenes, Pneumococcus, Streptococcus faecalis, etc.) are all resistant to this product. Anaerobic bacteria (Bacteroides), Mycobacterium tuberculosis, Rickettsia, viruses and fungi are also resistant to this product. The mechanism of action of this product is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins.