Hefei Limin Pharmaceutical Co., Ltd.

It is converted into flavine mononucleotide (FMN) and flavin adenine dinucleotide, both of which are important coenzymes for tissue respiration. It can also activate vitamin B6, participate in the conversion of tryptophan into niacin, and may be related to maintaining the integrity of red blood cells.

It is converted into flavine mononucleotide (FMN) and flavin adenine dinucleotide, both of which are important coenzymes for tissue respiration. It can also activate vitamin B6, participate in the conversion of tryptophan into niacin, and may be related to maintaining the integrity of red blood cells.

Vitamin B2 is converted into flavin mononucleotide (FMN) and flavin adenine dinucleotide, both of which are important coenzymes for tissue respiration. It can also activate vitamin B6 and convert amino acids into niacin, and may be related to maintaining the integrity of red blood cells.

Vitamin B2 is converted into flavin mononucleotide (FMN) and flavin adenine dinucleotide, both of which are important coenzymes for tissue respiration. It can also activate vitamin B6 and convert amino acids into niacin, and may be related to maintaining the integrity of red blood cells.

Vitamin B2 is converted into flavin mononucleotide (FMN) and flavin adenine dinucleotide, both of which are important coenzymes for tissue respiration. It can also activate vitamin B6 and convert amino acids into niacin, and may be related to maintaining the integrity of red blood cells.

This product is a competitive angiotensin converting enzyme inhibitor, which prevents angiotensin I from being converted into angiotensin II, thereby reducing peripheral vascular resistance and reducing water and sodium retention by inhibiting aldosterone secretion. This product can also dilate peripheral blood vessels by interfering with the degradation of bradykinin. For patients with heart failure, this product can also reduce capillary wedge pressure and pulmonary vascular resistance, increase cardiac output and exercise tolerance time.

This product is a dihydropyridine calcium channel blocker that inhibits transmembrane calcium influx in vascular smooth muscle and myocardium, but mainly acts on blood vessels, so it has strong vascular selectivity. It causes dilation of systemic blood vessels such as coronary arteries and renal arterioles, producing a hypotensive effect.

Trimethoprim (TMP) is an antibacterial agent, a lipophilic weak base, and its chemical structure belongs to the pyrimethamine class. It has antibacterial activity against Escherichia coli, Klebsiella, Proteus mirabilis, Salmonella, and Shigella, but has no obvious antibacterial effect on Streptococcus pneumoniae, Neisseria gonorrhoeae, and Neisseria meningitidis, and has no effect on Pseudomonas aeruginosa. The mechanism of action of this product is to interfere with bacterial folic acid metabolism. It mainly selectively inhibits the activity of bacterial dihydrofolate reductase, so that dihydrofolate cannot be reduced to tetrahydrofolate, and synthetic folic acid is the main component of nucleic acid biosynthesis. Therefore, this product prevents the synthesis of bacterial nucleic acids and proteins, and the binding of this product to bacterial dihydrofolate reductase is 50,000 to 60,000 times tighter than that to mammalian enzymes. The combination of this product and sulfonamides can double block the bacterial folic acid synthesis metabolism, have a synergistic effect, enhance the antibacterial activity of sulfonamides, and convert the antibacterial effect into a bactericidal effect, reducing the production of drug-resistant strains.

This product belongs to the macrolide antibiotics, which is the dodecyl sulfate of erythromycin propionate. It has antibacterial activity against Staphylococcus, various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. may also be sensitive to this product. This product also has antibacterial activity against various anaerobic bacteria except Bacteroides fragilis and Fusobacterium; it also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can pass through the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis. This product is only effective against bacteria with active division.