It has high antibacterial activity against common aerobic Gram-positive bacteria, such as Staphylococcus aureus (including those resistant to penicillin G), Staphylococcus epidermidis, β-hemolytic Streptococcus, viridans Streptococcus and Streptococcus pneumoniae. It has good antibacterial effect against anaerobic bacteria, including Clostridium tetani, Corynebacterium diphtheriae and Clostridium perfringens. It has no activity against Gram-negative bacteria such as Enterococcus, meningococci, Neisseria gonorrhoeae and Haemophilus influenzae, as well as fungi. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins and tetracyclines, and there is partial cross-resistance with macrolides. This product acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. It is generally an antibacterial agent, but at high concentrations, it also has a bactericidal effect on certain bacteria.

Lomeza is a broad-spectrum quinolone antibiotic that has bactericidal effects on Gram-negative bacteria, Gram-positive bacteria and some anaerobic bacteria. It has good antibacterial effects on methicillin-resistant Staphylococcus aureus, ampicillin-resistant influenza bacilli, pipemidic acid-resistant Escherichia coli and bacteria resistant to other drugs. Its antibacterial mechanism is to inhibit the activity of bacterial DNA helicase, thereby inhibiting bacterial DNA transcription and replication, and has bactericidal effects on a variety of Gram-positive and Gram-negative bacteria.

Adrenal cortex hormone drugs. It has anti-inflammatory, anti-allergic, anti-rheumatic and immunosuppressive effects. 1 Anti-inflammatory effect: Reduce and prevent tissue response to inflammation, inhibit inflammatory cell aggregation, phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. 2 Immunosuppressive effect: Prevent or inhibit cell-mediated immune response, reduce the number of T lymphocytes, monocytes, and eosinophils, reduce the ability of immunoglobulins to bind to cell surface receptors and inhibit interleukin synthesis and release, reduce the transformation of T lymphocytes to lymphoblasts and reduce the expansion of primary immune responses, reduce the passage of immune complexes through the basement membrane and reduce complement components and immunoglobulin concentrations.

1. Effect on water and electrolyte excretion: It can increase the excretion of water, sodium, chloride, potassium, calcium, magnesium, phosphorus, etc., mainly by inhibiting the active reabsorption of NaCl by the thick-walled segment of the renal tubular loop, reducing the osmotic pressure gradient difference of the medullary interstitial fluid, and reducing the reabsorption of water and electrolytes. At the same time, it may inhibit the reabsorption of Na+ and Cl- by the proximal and distal tubules, promote the secretion of K+ by the distal tubules, and increase the excretion of Ca2+ and Mg2+; short-term medication can increase uric acid excretion, while long-term medication can cause hyperuricemia. 2. Effect on hemodynamics: Furosemide can inhibit the activity of prostaglandin degrading enzymes, increase the content of prostaglandin E2, dilate blood vessels, increase renal blood flow, especially the deep blood flow of the renal cortex, which is of great significance in the diuretic effect. In addition, furosemide can dilate the pulmonary capacitance veins, reduce the permeability of pulmonary capillaries, reduce the amount of blood returning to the heart, and reduce the left ventricular end-diastolic pressure, which is helpful for the treatment of acute left heart failure and adult respiratory distress syndrome.

It has anti-cerebral ischemia effect, can improve brain edema in rats with multiple cerebral infarction, promote glial cell reaction, accelerate the absorption and organization of softening foci, and reduce neuronal lesions in the hippocampus; it has a protective effect on delayed neuronal damage in the hippocampus of gerbils with transient cerebral ischemia, can reduce the Ca2 content in brain tissue after ischemia, reduce the number of dead neurons, and increase neuronal density. It has anti-myocardial ischemia effect, can reduce the downward shift of the S-T segment of the electrocardiogram caused by acute myocardial ischemia in rats, and adjust the electrocardiogram inhomogeneity. It improves blood rheology, can reduce whole blood viscosity and plasma viscosity, reduce hematocrit and platelet aggregation rate, slow down erythrocyte sedimentation rate, and reduce fibrinogen content. It improves microcirculation, can reduce the morphological integral, flow integral, semi-circular integral, and overall integral of the nail fold microcirculation, reduce peri-loop exudation, reduce tube diameter, increase flow velocity, reduce red blood cell aggregation, reduce loop top congestion, increase loop clarity, and subside edema. It has the effect of lowering blood lipids, reducing total cholesterol, triglycerides, and low-density lipoprotein levels. It has the effect of resisting free radical damage, increasing the activity of superoxide dismutase in erythrocytes, reducing the content of malondialdehyde in plasma, and reducing the content of serum protein kinase C and aspartate aminotransferase.