Furen Pharmaceutical Group Co., Ltd.

It has antiprotozoan and obligate anaerobic effects. It has inhibitory effects on protozoa such as Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia. It has antibacterial effects on most anaerobic bacteria such as Bacteroides fragilis, Bacteroides melanin, other Bacteroides, Clostridium, Eubacteria, Fusobacterium, Haemophilus vaginalis, Peptococcus, Peptostreptococcus and Veillonella.

Azithromycin is a 15-membered macrolide antibiotic. In vitro tests have shown that it has antibacterial effects on a variety of common pathogens, including Gram-positive aerobic bacteria (such as Staphylococcus aureus, Streptococcus pyogenes, etc.), Gram-negative aerobic bacteria (such as Haemophilus influenzae, Moraxella catarrhalis, etc.), anaerobic bacteria (such as Bacteroides fragilis, etc.), sexually transmitted disease microorganisms (such as Treponema pallidum, Neisseria gonorrhoeae, etc.) and other microorganisms (such as Borrelia tenuissima, Mycoplasma pneumoniae, etc.). The mechanism of action is the same as that of erythromycin, mainly binding to the 50S subunit of the bacterial ribosome to inhibit RNA-dependent protein synthesis.

This product is a piperazine calcium channel antagonist that can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the intracellular cAMP concentration, inhibiting the release of histamine, 5-hydroxytryptamine, bradykinin and other biologically active substances, and also inhibiting the activation of complement C4.

This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. It has a killing effect on histolytica and a strong killing effect on trichomonas. It has a killing effect on anaerobic microorganisms, interferes with the growth and reproduction of bacteria, and eventually kills bacteria.

This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1-2 mg/L, the histolytica can undergo morphological changes in 6-20 hours and all are killed within 24 hours. When the concentration is 0.2 mg/L, the histolytica can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on anaerobic microorganisms, and the metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. Metronidazole is carcinogenic to some animals.