This product is a calcium supplement. Calcium can maintain the normal excitability of nerves and muscles and promote the secretion of acetylcholine by nerve endings. When serum calcium is low, the excitability of nerves and muscles may increase, resulting in convulsions. When blood calcium is too high, the excitability may decrease, resulting in weakness, etc. Calcium ions can improve the permeability of cell membranes, increase the density of capillaries, reduce exudation, and have an anti-allergic effect. Calcium ions can promote the calcification of bones and teeth. There is a competitive antagonism between high concentrations of calcium ions and magnesium ions, which can be used to rescue magnesium poisoning; calcium ions can react with fluoride to form insoluble calcium fluoride, which can be used to rescue fluoride poisoning.

This product is a semi-synthetic aminoglycoside antibiotic. It has strong antibacterial activity against aerobic Gram-negative bacteria. Its antibacterial spectrum is similar to that of gentamicin. It has good antibacterial effects on Escherichia coli, Pseudomonas aeruginosa, indole-negative and -positive Proteus, Klebsiella, Acinetobacter, Citrobacter, and some strains of Serratia and Enterobacter. It also has good antibacterial effects on Mycobacterium tuberculosis, atypical mycobacteria and Staphylococcus aureus (enzyme-producing and non-enzyme-producing strains). Other Gram-positive bacteria (including Streptococcus faecalis), anaerobic bacteria, Rickettsia, fungi and viruses are not sensitive to this product. This product is stable to aminoglycoside acetyltransferase AAC (3), so it can produce this enzyme. Strains resistant to kanamycin, gentamicin, tobramycin and sisomicin are sensitive to this product. This product can often achieve synergistic effects when used in combination with β-lactams. The mechanism of action of this product is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins.

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the hypothalamus, posterior pituitary and kidneys to maintain the stability of body fluid volume and osmotic pressure.

Selective calcium ion antagonists mainly inhibit the influx of extracellular calcium into arteriolar smooth muscle cells, selectively dilate arterioles, have no such effect on veins, do not cause postural hypotension, and have no significant inhibitory effect on the myocardium. While reducing renal vascular resistance, they do not affect the glomerular filtration rate and creatinine clearance rate, and the renal blood flow remains unchanged or even slightly increases, and has a natriuretic and diuretic effect. It can increase output and cardiac index, significantly reduce afterload, and has no significant effect on cardiac contractile function, preload, and heart rate.

Selective calcium ion antagonists mainly inhibit the influx of extracellular calcium into arteriolar smooth muscle cells, selectively dilate arterioles, have no such effect on veins, do not cause postural hypotension, and have no significant inhibitory effect on the myocardium. While reducing renal vascular resistance, they do not affect the glomerular filtration rate and creatinine clearance rate, and the renal blood flow remains unchanged or even slightly increases, and has a natriuretic and diuretic effect. It can increase output and cardiac index, significantly reduce afterload, and has no significant effect on cardiac contractile function, preload, and heart rate.