Di'ao Group Chengdu Pharmaceutical Co., Ltd.

This product is a broad-spectrum antibacterial agent, with bactericidal effect at high concentrations. It has certain antibacterial effects on Streptococcus pneumoniae, hemolytic Streptococcus, Streptococcus viridans and some Staphylococci, Clostridium perfringens, Bacillus anthracis, Yersinia pestis, Corynebacterium diphtheriae, Clostridium tetani, Brucella, Haemophilus influenzae, Campylobacter, Vibrio cholerae, and also has inhibitory effects on Rickettsia, Mycoplasma, Chlamydia, Spirochete, and some protozoa. It has better effect on Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. It has certain antibacterial activity against Neisseria gonorrhoeae and Neisseria meningitidis, but penicillin-resistant gonococci are also resistant to tetracycline. It has no antibacterial activity against Pseudomonas aeruginosa. It has certain antibacterial effect on some anaerobic bacteria, but it is far inferior to metronidazole, clindamycin and chloramphenicol. The mechanism of action is that the drug can specifically bind to the A position of the bacterial ribosome 30S subunit, preventing the binding of aminoacyl-tRNA at this position, thereby inhibiting the growth of peptide linkages and affecting the synthesis of bacterial proteins.