Tandospirone is an antianxiety drug that selectively acts on the 5-HT1A receptor in the brain. Animal experiments have shown that tandospirone has comparable antianxiety effects to diazepam. Animal model experiments on psychosomatic diseases have shown that tandospirone can inhibit the pressor response caused by hypothalamic stimulation and the increase in plasma renin activity caused by electric shock stress, and inhibit the occurrence of gastric ulcers caused by psychological stress and the loss of appetite caused by forced immersion stress.

Tizanidine is a central alpha 2 adrenergic receptor agonist, which may reduce tonic spasm by enhancing the presynaptic inhibition of motor neurons. Animal experiments have shown that tizanidine has no direct effect on skeletal muscle fibers and neuromuscular junctions, and has a weak effect on monosynaptic spinal reflexes. Tizanidine has the strongest effect on multisynaptic pathways, and these effects are believed to be related to the reduced facilitation of spinal motor neurons.

Tizanidine is a central α2-adrenergic receptor agonist, which may reduce tonic spasm by enhancing the presynaptic inhibition of motor neurons. Animal experiments have shown that tizanidine has no direct effect on skeletal fibers and neuromuscular junctions, and has a weak effect on monosynaptic spinal reflexes. Tizanidine has the strongest effect on multisynaptic pathways, and these effects are believed to be related to the reduced facilitation of spinal motor neurons.

Tizanidine is a central α2-adrenergic receptor agonist that may reduce tonic spasms by enhancing presynaptic inhibition of motor neurons. Animal experiments have shown that tizanidine has no direct effect on skeletal muscle fibers and neuromuscular junctions, and has a weak effect on monosynaptic spinal reflexes. Tizanidine has the strongest effect on multisynaptic pathways, and these effects are believed to be related to the reduced facilitation of spinal motor neurons.