Harbin Pharmaceutical Group Pharmaceutical Factory No.6

A mild peripheral vasodilator with the pharmacological effects of niacin and inositol and lipid-lowering effects; the vasodilatory effect is mild and long-lasting, without the side effects of flushing and stomach discomfort; it selectively dilates blood vessels in lesions and sensitive areas stimulated by cold; it has the effects of dissolving blood clots, anti-coagulation, anti-fatty liver, and reducing capillary fragility.

Tetracycline antibiotics, broad-spectrum antibacterial agents, have bactericidal effects at high concentrations. It inhibits peptide chain growth and bacterial protein synthesis by specifically binding to the A position of the bacterial ribosome 30S subunit. It is sensitive to many Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes; it is better for Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. Other sensitive bacteria include Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. Animal experiments have confirmed that this product is teratogenic, and in vitro experiments have shown that it may be mutagenic at a certain concentration.

This product is a broad-spectrum antibacterial agent with bactericidal effect at high concentrations. Many Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product is better than Gram-positive bacteria for Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, and Yersinia are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to doxycycline. There is cross-resistance between this product and different varieties of tetracycline antibiotics. The mechanism of action of this product is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome, inhibit the growth of the peptide chain and affect the synthesis of bacterial proteins. Animal experiments have confirmed that this product is teratogenic. In vitro experiments have shown that this product may cause mutations at a certain concentration.

Tetracycline antibiotics. This product is a broad-spectrum antibacterial agent with bactericidal effects at high concentrations. Many Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product is more effective against Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, and Yersinia are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to doxycycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have become seriously resistant to this product, including Gram-positive bacteria such as Staphylococcus and most Gram-negative bacilli. There is cross-resistance between this product and different varieties of tetracycline antibiotics. The mechanism of action of this product is that the drug can specifically bind to the A position of the bacterial ribosome 30S subunit, inhibiting the growth of the peptide chain and affecting the synthesis of bacterial protein. Animal experiments have confirmed that this product is teratogenic. In vitro tests have shown that this product may be mutagenic at a certain concentration.

Anti-angina drug. This product belongs to the nitrate compound, which has the effect of preventing the free calcium ions in cells, increasing the permeability of cell membranes to potassium ions, dilating coronary blood vessels, continuously increasing coronary blood flow, and inhibiting coronary artery spasm. When dilating coronary blood vessels, it does not affect blood pressure, heart rate, myocardial contractility, and myocardial oxygen consumption. This product also has the effect of inhibiting platelet aggregation and preventing thrombosis.