It is a coenzyme necessary for many metabolic processes in the body and an important coenzyme for tissue respiration.

An important coenzyme component required for tissue respiration

It is a cofactor for many enzymes and is involved in the metabolism of amino acids and fats.

It is a component of coenzymes I and II and is necessary for lipid metabolism, oxidation of tissue respiration, and glycogenolysis.

It is a precursor of coenzyme A and is involved in the metabolism of carbohydrates, fats, and proteins.

The antibacterial spectrum is similar to that of rifampicin. It has good antibacterial activity against tuberculosis and leprosy. When the dosage is 1/3 of that of rifampicin, similar or higher efficacy can be achieved. It has a good effect on Staphylococcus aureus and has certain antibacterial activity against some Escherichia coli. In addition, it also has an inhibitory effect on Chlamydia trachomatis.

This product is a broad-spectrum antibacterial agent, with bactericidal effect at high concentrations. It has certain antibacterial effects on Streptococcus pneumoniae, hemolytic Streptococcus, Streptococcus viridans and some Staphylococci, Clostridium perfringens, Bacillus anthracis, Bacillus plague, Corynebacterium diphtheriae, Clostridium tetani, Brucella, Haemophilus influenzae, Campylobacter, Vibrio cholerae, etc. It also has inhibitory effects on Rickettsia, Mycoplasma, Chlamydia, Spirochete, and some protozoa. It has better effects on Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, etc. are also sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae and Neisseria meningitidis, but penicillin-resistant gonococci are also resistant to tetracycline. This product has no antibacterial activity against Pseudomonas aeruginosa. It has a certain antibacterial effect on some anaerobic bacteria, but it is far less effective than metronidazole, clindamycin and chloramphenicol, so it is not used clinically. Due to the widespread use of tetracyclines for many years, common clinical pathogens, including Gram-positive bacteria such as Staphylococcus and Gram-negative bacteria such as Enterobacter, have serious tetracycline resistance, and there is cross-resistance between similar varieties. The mechanism of action of this product is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome, preventing the binding of aminoacyl-tRNA at this position, thereby inhibiting the growth of peptide linkages and affecting the synthesis of bacterial proteins.

This product belongs to the macrolide antibiotics, which is the dodecyl sulfate of erythromycin propionate. It has antibacterial activity against Staphylococcus, various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. may also be sensitive to this product. This product also has antibacterial activity against various anaerobic bacteria except Bacteroides fragilis and Fusobacterium; it also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can pass through the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis. This product is only effective against bacteria with active division.