This product is a semi-synthetic ergot alkaloid derivative. It has α receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It can promote the conversion of neurotransmitter dopamine to enhance nerve conduction, strengthen brain protein biosynthesis, and improve brain function. Toxicity tests failed to show that nicergoline has teratogenic effects.

It has both histamine H1 receptor antagonism and the effect of inhibiting the release of allergic reaction mediators. It not only has a strong anti-allergic effect, but also has a longer duration of efficacy. Therefore, it is more effective in preventing various bronchial asthma attacks and exogenous asthma than endogenous asthma.

This product is a non-sedating, long-acting tricyclic antihistamine and an active metabolite of loratadine. It can relieve symptoms related to allergic rhinitis or chronic idiopathic urticaria by selectively blocking peripheral H1 receptors. In addition, in vitro studies have shown that this product can inhibit the release of histamine from human mast cells. Animal studies have shown that this product is not easy to pass through the blood-brain barrier.

It has a broad spectrum of antimicrobial effects, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis; it has antibacterial effects on Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis, etc. Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus are usually resistant to it. This product reversibly binds to the 50S subunit of the bacterial ribosome, inhibits protein synthesis, and is completely cross-resistant with chloramphenicol. It also has a strong immunosuppressive effect, which is about 6 times stronger than chloramphenicol.