Qinghai Pharmaceutical Co., Ltd.

This product is a dried yeast body, rich in B vitamins, and has an auxiliary therapeutic effect on indigestion.

It has high antibacterial activity against common aerobic Gram-positive bacteria, such as Staphylococcus aureus (including those resistant to penicillin G), Staphylococcus epidermidis, β-hemolytic Streptococcus, viridans Streptococcus and Streptococcus pneumoniae. It has good antibacterial effect on anaerobic bacteria, including Clostridium diphtheriae, and Clostridium perfringens. It has no activity against Gram-negative bacteria such as enterococci, meningococci, Neisseria gonorrhoeae, and Haemophilus influenzae, as well as fungi. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins and tetracyclines, and there is partial cross-resistance with macrolides. It acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. It is generally an antibacterial agent, but at high concentrations, it also has a bactericidal effect on certain bacteria.

It has high antibacterial activity against common aerobic Gram-positive bacteria, such as Staphylococcus aureus (including those resistant to penicillin G), Staphylococcus epidermidis, beta-hemolytic Streptococcus, viridans Streptococcus and Streptococcus pneumoniae. It has good antibacterial effect on anaerobic bacteria, including Clostridium diphtheriae, and Clostridium perfringens. It has no activity against Gram-negative bacteria such as enterococci, meningococci, Neisseria gonorrhoeae, and Haemophilus influenzae, as well as fungi. There is no cross-resistance with penicillin, chloramphenicol, cephalosporins and tetracyclines, and there is partial cross-resistance with macrolides. It acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. It is generally an antibacterial agent, but at high concentrations, it also has a bactericidal effect on certain bacteria.

After oral administration, it is completely absorbed from the gastrointestinal tract, and the peak blood concentration is reached 1 to 4 hours after taking the drug. It is mainly filtered through the glomeruli and secreted by the renal tubules. The urine drug concentration is significantly higher than the blood drug concentration. It can be widely distributed in the tissues and body fluids of the whole body and penetrate the blood-cerebrospinal fluid barrier to reach the therapeutic concentration. It can also cross the blood-placental barrier, enter the fetal blood circulation and can be secreted into breast milk.

After oral administration, it is completely absorbed from the gastrointestinal tract, and the peak blood concentration is reached 1 to 4 hours after taking the drug. It is mainly filtered through the glomeruli and secreted by the renal tubules. The urine drug concentration is significantly higher than the blood drug concentration. It can be widely distributed in the tissues and body fluids of the whole body and penetrate the blood-cerebrospinal fluid barrier to reach the therapeutic concentration. It can also cross the blood-placental barrier, enter the fetal blood circulation and can be secreted into breast milk.

It has an antibacterial effect only on Mycobacterium tuberculosis. This product is a congener of para-aminobenzoic acid (PABA), which inhibits the growth and reproduction of Mycobacterium tuberculosis by competitively inhibiting the synthesis of folic acid.