Kaifeng Pharmaceutical (GROUP) Co., Ltd.

This product is a drug for increasing white blood cells. Vitamin B4 is a component of nucleic acid and participates in the synthesis of RNA and DNA in the body. When white blood cells are deficient, it can promote white blood cell proliferation.

Adrenal cortex hormone drugs. It has anti-inflammatory, anti-allergic, anti-rheumatic and immunosuppressive effects. 1. Anti-inflammatory effect: Reduce and prevent tissue response to inflammation, thereby reducing the manifestations of inflammation. It can inhibit the accumulation of inflammatory cells, including macrophages and leukocytes, at the site of inflammation, and inhibit phagocytosis, the release of lysosomal enzymes, and the synthesis and release of inflammatory chemical mediators. 2. Immunosuppressive effect: including preventing or inhibiting cell-mediated immune responses, delayed allergic reactions, reducing the number of T lymphocytes, monocytes, and eosinophils, reducing the ability of immunoglobulins to bind to cell surface receptors, and inhibiting the synthesis and release of interleukins, thereby reducing the transformation of T lymphocytes into lymphoblasts.

It has no antibacterial activity in vitro. After oral administration, it is hydrolyzed into chloramphenicol by pancreatic lipase and absorbed into the body to exert its antibacterial effect. It has antibacterial activity against aerobic Gram-negative and Gram-positive bacteria, anaerobic bacteria, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on influenza bacilli, Streptococcus pneumoniae and Neisseria meningitidis; it only has antibacterial effects on Staphylococcus aureus, Streptococcus pyogenes, etc. Drug-resistant bacteria include Pseudomonas aeruginosa, Acinetobacter, etc. It exerts its effect by inhibiting bacterial protein synthesis.

This product is a semi-synthetic 14-membered macrolide antibiotic. Its antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. It is slightly less effective than erythromycin against Gram-positive bacteria, but stronger than erythromycin against Legionella pneumophila. Its antimicrobial effect against Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor (P site), blocking the transfer RNA (t-RNA) from binding to the P site, and also blocking the transfer of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis.

It selectively excites the medullary respiratory center and can also act on the carotid body and aortic body chemoreceptors to reflexively excite the respiratory center and increase the respiratory center's sensitivity to carbon dioxide, deepening and accelerating breathing. It has a weak excitatory effect on the vasomotor center. Excessive doses can cause convulsions.