It is a broad-spectrum anthelmintic that can inhibit the intestinal parasites' glucose uptake, leading to the depletion of glycogen in the worms and reducing the formation of adenosine triphosphate in the worms. However, it does not affect the host's blood glucose level. Ultrastructural observation showed that mebendazole caused the degeneration of microtubules in the cytoplasm of the worm's membrane cells and intestinal cells, resulting in the accumulation of Golgi endocrine granules. Transport blockage, cytoplasmic dissolution, and complete degeneration of absorptive cells caused the death of the worms. Mebendazole has the effect of completely killing hookworm eggs and whipworm eggs and partially killing ascarid eggs. In vitro tests have shown that 5 mg/L can inhibit the development of hookworm larvae.

It can selectively inhibit succinate dehydrogenase in the muscles of the worm, so that fumaric acid cannot be reduced to succinic acid, thereby affecting the anaerobic metabolism of the muscles of the worm and reducing energy production. In addition, the drug may have an inhibitory effect on the microtubule structure of the worm. Levamisole also has immune regulation and immune stimulation functions.

It can catalyze the cleavage of peptide bonds in protein molecules, decompose proteins, peptides, lipids, amides and other substances, and has anti-inflammatory and anti-edema effects.

Not yet clear

After being absorbed by the digestive tract, it is converted into active metabolites in the body. Its active metabolites exert analgesic, anti-inflammatory and antipyretic effects by inhibiting the synthesis of prostaglandins.

It can catalyze the cleavage of peptide bonds in protein molecules, decompose proteins, peptides, lipids and amides, and has anti-inflammatory and anti-edema effects.