Lodays Pharmaceutical(Hubei) Co., Ltd.

A selective 5-HT3 receptor antagonist, it has a significant inhibitory effect on nausea and vomiting caused by anticancer drugs such as cisplatin. Animal studies have shown that the affinity of azasetron hydrochloride for the 5-HT3 receptor in the rat cerebral cortex is about 410 times stronger than that of metoclopramide, twice that of ondansetron, and basically the same as that of granisetron.

No specific pharmacological action is mentioned

1. Inhibit plasminogen activators, so that plasminogen cannot be activated into plasmin, thereby inhibiting the dissolution of fibrin and producing a hemostatic effect; 2. Promote the release of active substances by platelets, enhance platelet aggregation and adhesion, shorten coagulation time, and produce a hemostatic effect; 3. Enhance capillary resistance, reduce capillary permeability, and thus reduce bleeding.

This product is a proton pump inhibitor of gastric parietal cells, which can specifically inhibit the secretory microtubules and H, K-ATPases on the tubular vesicles in the cytoplasm of the parietal cell apical membrane, thereby effectively inhibiting the secretion of gastric acid. It can not only non-competitively inhibit the gastric acid secretion caused by gastrin, histamine, choline, food, and stimulation of the vagus nerve, but also inhibit part of the basic gastric acid secretion that is not affected by choline or H2 receptor blockers. It also has a strong and lasting inhibitory effect on the gastric acid secretion caused by dibutyl cyclic adenosine monophosphate (DCAMP) stimulation that cannot be inhibited by H2 receptor antagonists. In addition, this product also has an inhibitory effect on the secretion of pepsin, has no obvious change in gastric mucosal blood flow, and does not affect body temperature, gastric cavity temperature, arterial blood pressure, venous hemoglobin, arterial oxygen partial pressure, carbon dioxide partial pressure and arterial blood pH.

Methionine is one of the eight essential amino acids for the human body. It cannot be synthesized in the human body and must be supplemented from outside. Methionine combines with ATP in the human body to generate S-adenosine. It can promote the methylation of liver cell membrane phospholipids, reduce intrahepatic bile stasis, and enhance the transsulfurization effect. It is beneficial for liver cells to restore normal physiological functions, promote the disappearance of jaundice and the recovery of liver function. By supplying methyl groups, it promotes the synthesis of choline, promotes liver fat metabolism, protects the liver and detoxifies.

Vitamin B1 combines with pyrophosphate in the body to form a cocarboxylase, which participates in the oxidative decarboxylation reactions of pyruvate and α-ketoglutarate in carbohydrate metabolism and is necessary for carbohydrate metabolism.