Roxithromycin Capsules

This product is a semi-synthetic 14-membered macrolide antibiotic. Its antibacterial spectrum and antimicrobial effect are basically similar to those of erythromycin. It is slightly less effective than erythromycin against Gram-positive bacteria, but stronger than erythromycin against Legionella pneumophila. Its antimicrobial effect against Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor (P site), blocking the transfer RNA (t-RNA) from binding to the P site, and also blocking the transfer of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis.

Active ingredient: Roxithromycin.

This product is a capsule, and the contents are white or off-white powder and granules.

This product is suitable for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae; urethritis and cervicitis caused by Chlamydia trachomatis; skin and soft tissue infections caused by sensitive bacteria.

Take orally on an empty stomach. The general course of treatment is 5 to 12 days. Adults can take 150 mg twice a day or 300 mg once a day. Children can take 2.5 to 5 mg/kg twice a day.

The main adverse reactions are gastrointestinal reactions such as abdominal pain, diarrhea, nausea, and vomiting, but the incidence is significantly lower than that of erythromycin. Occasionally, there are rash, itchy skin, dizziness, headache, abnormal liver function (increased ALT and AST), and decreased peripheral blood cells.

Roxithromycin capsules are contraindicated in patients who are allergic to erythromycin or other macrolide drugs.

Precautions for children: Not clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Less than 0.05% of the dose is excreted into breast milk. Although there are reports that it has little effect on infants, it is still necessary to consider whether to stop breastfeeding. Precautions for the elderly: If the pharmacokinetics in the elderly do not change significantly, there is no need to adjust the dose.

1. It should not be used in combination with ergotamine, dihydroergotamine, bromocriptine, terfenadine, ketoconazole and cisapride. 2. It has little effect on the metabolism of aminophylline and has little effect on carbamazepine, warfarin, ranitidine and other antacids.

Keep away from light, sealed and stored in a dry place.

150 mg

24 months

Shaanxi Xinfenghe Pharmaceutical Co., Ltd.

• Founded in:

  2017-08-15

• Address:

  Xingye 6th Road, Southern Industrial Park, New District, Tongchuan City, Shaanxi Province (Yaowang Health Industry Incubation Park)

• Tax NO.:

  91610201MA6X6B7C37

• Registered Funds:

  93.75 million yuan

• Email:

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